摘要
目的探讨P3T腹部模块(P3TTM Abdomen MEDRAD)个性化优化对比剂注射方案在肝脏CT成像中的作用。方法收集接受上腹部CT增强检查的91例患者,随机分为两组:试验组(n=49)采用P3T腹部模块个性化设计对比剂注射方案;对照组(n=42)对比剂用量为1.5ml/kg体质量;测量并比较动脉期和门静脉期肝实质和门静脉期门静脉的CT值,分析试验组体质量、对比剂用量与肝实质、门静脉CT值间的相关性,比较两组肝细胞癌在动脉期及门静脉期的强化程度。结果试验组和对照组的肝动脉期肝实质、门静脉期肝实质的CT值差异无统计学意义(P>0.05),而对比剂剂量和门静脉的CT值差异均有统计学意义(P均<0.01);试验组双期肝实质CT值均与体质量、对比剂使用剂量间均呈负相关(P均<0.01);两组肝细胞癌在动脉期及门静脉期增强程度差异无统计学意义(P均>0.05)。结论P3T腹部模块可根据患者体质量自动计算对比剂剂量,在不影响图像质量的前提下降低对比剂用量。
Objective To observe the effect of individually tailored protocol for the injection of contrast medium （CM） adjusted by personalized patient protocol technology （P3T） abdomen module （P3TTM Abdomen MEDRAD） on CT imaging of liver. Methods Ninety-one patients who underwent contrast enhanced CT scanning of upper abdomen were randomly divided into 2 groups： Group A （n=49） used P3TTM abdomen module to design individually tailored protocol for the injection of CM, group B （n=42） used fixed dose at 1.5 ml/kg. CT values of liver parenchyma and portal vein were measured in the arterial phase （AP） and the portal venous phase （PVP）, and were compared between the two groups. The correlation between weight, dose of CM and attenuation values of the liver parenchyma （AP and PVP） in group A were observed, respectively. The degrees of contrast enhancement of hepatocellular carcinoma （HCC） both in AP and PVP were compared between two groups. Results There was no statistical difference in attenuation values of the liver parenchyma （AP and PVP, P〉0.05） between the two groups, but statistical difference was found in mean CM dose and mean attenuation values of the portal vein （all P〈0.01）. CT values of liver parenchyma were negatively correlated with weight and dose of CM, respectively. The degrees of HCC contrast enhancement both in AP and PVP were not statistical different between the two groups （both P〉0.05）. Conclusion P3TTM abdomen module can automatically calculate the dose of CM according to patient-specific parameters （such as weight）, therefore reduce dose of CM as much as possible without obvious impact on imaging quality.
出处
《中国医学影像技术》
CSCD
北大核心
2013年第8期1379-1383,共5页
Chinese Journal of Medical Imaging Technology
