摘要
目的:探讨Ⅱb期宫颈癌术前同步放化疗近期临床疗效。方法:将58例组织学明确的Ⅱb期宫颈癌患者分为A组28例,术前给予新辅助化疗;B组30例,术前同步放化疗。比较2组的临床疗效、手术时间、术中出血量、膀胱功能恢复等指标。结果:B组近期临床有效率为90.00%,高于A组的67.86%(P<0.05);2组手术时间、术中出血量及膀胱功能恢复时间差异均无统计学意义(P>0.05);术前放化疗能降低子宫旁浸润和淋巴结转移率(P<0.05)。结论:术前同步放化疗能提高Ⅱb期宫颈癌近期临床疗效,提高手术切除率,减少子宫旁浸润和盆腔淋巴结转移,是一种可选的治疗方法。
Objective： To explore the curative effects of preoperative concurrent chemoradiotherapy for Ⅱb cervical cancer.Methods： Fifty-eight cases with Ⅱb cervical cancer were divided into group A（28 cases） and group B（30 cases）.Group A and B were treated with chemotherapy and concurrent chemoradiotherapy before operation,respectively.The clinical effects,adverse reactions,operative time,blood loss,pathological features and recovery time of bladder function in two groups were analyzed.Results： The clinical effective rate in group B（90.00%） was higher than that in group A（67.86%）（P 0.05）.The differences of operative time,blood loss and recovery time of bladder function in two groups were not statistical significante（P 0.05）.The preoperative chemoradiotherapy could decrease parametrial invasion and pelvic lymphnode metastasis（P 0.05）.Conclusions： The preoperative concurrent chemoradiotherapy for Ⅱb cervical cancer can improve the clinical effects and resectable rate and decrease parametrial invasion and pelvic lymphnode metastasis,which is a practicable means.
出处
《蚌埠医学院学报》
CAS
2013年第8期985-986,989,共3页
Journal of Bengbu Medical College
关键词
子宫颈肿瘤
同步放化疗
疗效
cervical cancer
concurrent chemoradiotherapy
effect
