摘要
目的探讨无创正压通气技术(BiPAP)在肺心病合并Ⅱ型呼吸衰竭治疗中的应用价值。方法选取慢性肺心病合并Ⅱ型呼吸衰竭患者40例,随机分为对照组和观察组,每组20例。对照组给予低流量吸氧、常规抗感染、解痉平喘、纠正水电解质紊乱等基础治疗,观察组在此基础上加用无创正压通气治疗。观察2组患者治疗前和治疗后24 h的临床表现、动脉血气变化、生命体征和不良反应。结果治疗后24 h,2组RR、HR均有所降低,差异有统计学意义(P<0.01);治疗后,观察组Sa(O2)显著升高,与对照组比较差异有统计学意义(P<0.01);Pa(CO2)和Pa(O2)明显下降,2组比较差异有统计学意义(P<0.05);观察组pH值与对照组相比,差异有统计学意义(P<0.05)。结论 BiPAP可有效改善肺心病合并Ⅱ型呼吸衰竭患者的临床症状,减轻心脏负荷,且不良反应较少,值得临床推广应用。
Objective To observe noninvasive positive pressure ventilation technology（BiPAP） in the treatment of cor pulmonale combined with type 2 respiratory failure.Methods Forty patients with chronic cor pulmonale combined with type 2 respiratory failure were selected and randomly divided into control group（n=20） and observation group（n=20）.The control group received routine treatment of low flow oxygen and routine anti-infection to relieve spasmolysis and asthma and correct water and electrolyte disorder.The observation group,on the basis of the routine treatment of the control group,received noninvasive positive pressure ventilation.Clinical manifestations,arterial blood gas changes and adverse reactions of the two groups before and 24 hours after treatment were observed.Results Twenty-four hours after treatment,RR and HR of the two groups were reduced and the differences were statistically significant（P0.01）.Sa（O2） of the observation group increased significantly after treatment.The difference of the two groups was statistically significant（P0.01）.Pa（CO2） and Pa（O2） decreased markedly.The differences of the two groups were statistically significantly（P〈0.05）.The difference of pH value between the observation group and the control group was statistically significant（P〈0.05）.Conclusion BiPAP can effectively improve clinical symptoms of cor pulmonale patients combined with type 2 respiratory failure and reduce the cardiac load with less adverse reactions.Thus it is worthy of wide clinical application.
出处
《实用临床医药杂志》
CAS
2013年第13期57-59,共3页
Journal of Clinical Medicine in Practice
关键词
正压通气
肺心病
呼吸功能不全
positive pressure ventilation
cor pulmonale
respiratory insufficiency
