期刊文献+

卵巢高钙血症型小细胞癌1例并文献复习 被引量:5

下载PDF
导出
摘要 目的探讨卵巢高钙血症型小细胞癌(ovarian small cell carcinoma hypercalcemic type,OSCCHT)的临床病理特征、诊断及鉴别诊断。方法观察1例OSCCHT患者的临床资料、组织形态、免疫表型,并结合文献分析其临床病理特征。结果患者FIGO分期Ⅲc期。镜下瘤细胞呈弥漫片状、岛状、梁状、条索状排列,可见大片坏死。局部肿瘤细胞形成滤泡样腔隙,腔内含嗜酸性液体。肿瘤细胞有大细胞和小细胞两种成分,以小细胞为主,部分细胞呈横纹肌样。瘤细胞核分裂象多见。免疫表型:CK(AE1/AE3)、EMA均阳性,CD99、Syn个别细胞弱阳性,α-inhibin、CgA、NSE均阴性。网状纤维染色阴性。结论 OSCCHT高度恶性,为避免误诊,在诊断年轻女性的卵巢肿瘤时,除考虑上皮来源、性索间质来源、生殖细胞来源以外,还应考虑杂类肿瘤。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2013年第8期911-913,共3页 Chinese Journal of Clinical and Experimental Pathology
  • 相关文献

参考文献12

  • 1Scully R E. Tumours of the ovary and maldeveloped gonads [ M ]// Atlas of tumor pathology. Washington D C : AFIP, 1979 : 316 - 7.
  • 2喻林,杨文涛,张廷璆.伴有大细胞成分的卵巢高钙血症型小细胞癌1例[J].临床与实验病理学杂志,2008,24(2):251-252. 被引量:5
  • 3陈雅卿,楼洪坤,方铣华.原发性卵巢小细胞癌四例[J].中华肿瘤杂志,2005,27(12):758-758. 被引量:8
  • 4王琼书,张蔚,赵小红,刘元姣.原发性卵巢小细胞癌——1例报道并复习文献[J].罕少疾病杂志,2001,8(1):4-5. 被引量:6
  • 5Walt H, Homung R, Fink D, et al. Hypercalcemic-type of small cell carcinoma of the ovary: characterization of a new tumor line [J]. Anticancer Res, 2001,21 (5) :3253 -9.
  • 6McCluggage W G, Oliva E, Connolly L E, et al. An immunohisto- chemical analysis of ovarian small cell carcinoma of hypercalcemic type[J]. Int J Gynecol Pathol, 2004,23(4):330-6.
  • 7TavassoliFA,DevileeP,著.乳腺及女性生殖器官肿瘤病理系和遗传学[M].程虹,主译.北京:人民卫生出版社,2006:226-7.
  • 8Stephens B, Stephen P A, Han H Y, et al. Molecular character- ization of a patient' s small cell carcinoma of the ovary of the hyper- calcemic type[J]. J Cancer, 2012,3:58 - 66.
  • 9Young R H, Oliva E, Scully R E. Small-cell carcinoma of the ova- ry, hypercalcemic type: a clinicopathological analysis of 150 cases [J]. AmJSurgPathol, 1994,18(11) :1102 -16.
  • 10McCluggage W G. Ovarian neoplasms composed of small round cells: a review[J]. Adv Anat Pathol, 2004,11 (6) :288 -96.

二级参考文献14

  • 1McCluggage WG,Oliva E,Connolly LE,et al.An immunohistochemical analysis of ovarian small cell carcinoma of hypercalcemic type.Int J Gynecol Pathol,2004,23:330-336.
  • 2Sukumvanich P,Einstein M,Wagner B,et al.Recurrent small cell lung cancer presenting as bilateral adnexal masses.Gnecol Oncol,2005,96:232-234.
  • 3Enrique Hernandez MD,Barbara F,Atkinson MD,主编 .袁耀萼主译 .临床妇科病理学[M].北京:人民卫生出版社 , 1998.391~ 396.
  • 4Mcmahon JT,Hart WR.Ultrastructural analysis of small cell carcinoma of ovary[J].AmJ Clin Pathol,1988,90:523.
  • 5Ulbright TM.Poorly differentiated (small Cell)carcinoma of ovary in youngwomen[J].HumPathol,1987,18:175.
  • 6AguirreP.Ovariansmallcellcarcinoma:histogeneticconsiderationbasedonimmunohistochemicalandother[J].AmJClinPathol,1989,92:149.
  • 7Eichhorn JH,Young RH,ScullyRE.Primary ovarian small cell carcinoma of pulmonary type:a clinical-pathologic,immunohistologic and flow cytometric analysis of 11 cases[J].AmJSurgPathol,1992,16:926~927. Am J Surg Pathol,1992,16:926~ 927.
  • 8Scully RE.Small cell carcinoma of hypercalcemia type[J].Int J Gynecolpathol,1993,12:148~ 152.
  • 9Dicker GR.Small cell carcinoma of ovary with hypercalcemia a report ofeleven[J].1982,49:188.
  • 10Taraszewski R.Case report:small cell carcinoma ofovary[J].GynecolOncol,1991,41:149.

共引文献14

同被引文献42

  • 1杨佳欣,沈铿,孙智晶,黄惠芳,潘凌亚,吴鸣,郎景和.原发性卵巢小细胞癌六例临床分析[J].中华妇产科杂志,2006,41(7):483-484. 被引量:13
  • 2Dickersin GR,Kline IW,Scully RE.Small cell carcinoma of the ovary with hypercalcemia:a report of 11 cases[J].Cancer,1982,49(1):188-197.
  • 3McCluggage WG,Oliva E,Connolly LE,et al.An Immunohistochemical analysis of ovarian small cell carcinoma of hypercalcemic type[J].Int J Gynecol Pathol,2004,23(4):330-336.
  • 4Walt H,Homung R,Fink D.Hypercalcemic-type of small cell carcinoma of the ovary:characterization of a new tumor line[J].Anticancer Res,2001,21(5):3253-3259.
  • 5Young R,Oliva E,Scully RE.Small cell carcinoma of the ovary,hypercalcemic type:a clinicopathological analysis of 150 cases[J].Am J Surg Pathol,1994,18(11):1102-1116.
  • 6Chen L,Dinh TA,Haque A.Small cell carcinoma of the ovary with hypercalcemia and ectopic parathyroid hormone production[J].Arch Pathol Lab Med,2005,129(4):531-533.
  • 7Powell JL,McAfee RD,McCoy RC,et al.Uterine and ovarian conse-rvation in advanced small cell carcinoma of the ovary[J].Obster Gynecol,1998,91(5):846-848.
  • 8李冬洁(综述,石群立(审校),黄文斌(审校).卵巢恶性小圆细胞肿瘤的诊断和鉴别诊断[J].医学研究生学报,2007,20(12):1314-1317. 被引量:7
  • 9Bahri M, Lahmar R, Ben S H, et al. Small cell carcinoma of the ovary[J]. Cancer Radiother, 2014,18(3):198-200.
  • 10Scully R E. Tumors of the ovary and maldeveloped gonads. Atlas of tumor pathology[M]. Washington D C: American Regist Pathol, 1979:316-7.

引证文献5

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部