摘要
目的探讨C反应蛋白(CRP)、心肌酶、高敏肌钙蛋白T(hs-cTnT)联合检测对手足口病病情评价及预后评估的临床应用价值。方法 196例手足口患儿根据病情分为高危组(59例)、低危组(137例),并以62例同期健康体检儿童为对照,比较各组CRP、心肌酶、hs-cTnT的血清浓度及异常率情况。结果手足口病高危组与低危组及正常对照组CRP、心激酶、hscTnT血清水平及异常率比较差异均有统计学意义(P<0.05);高危组CRP与心肌酶、hs-cTnT均呈正相关,其中以hs-cTnT、CK-MB相关系数较高。结论对手足口病心肌损伤的早期诊断和监测是防止病情恶化的关键,联合CRP、心肌酶、hs-cTnT的检测对手足口病心肌损伤的防治有重要的临床意义。
Objective To investigate the clinical value of joint detection of C-reactive protein （CRP）, heart kinase, high-sensitivity troponin T （hs-cTnT） in the evaluation and prognosis of hand-foot-mouth disease. Methods One hundred and ninety-six children with hand-foot-mouth disease were divided into high-risk group （59 cases）, low-risk group （137 cases）, and another 62 healthy children were chosen as control group. CRP, heart kinase, hs-cTnT serum concentration and abnormal rate were compared between each two groups. Results CRP, heart kinase, hs-cTnT serum levels and abnormal rate of the high-risk group, the low-risk group and the normal control group were different and the differences had statistical significance （P 〈 0.05）. In the high-risk group, CRP and cardiac enzymes, hs-cTnT showed a positive correlation, in which hs-cTnT, CK- MB had a high correlation coefficient. Conclusion Early diagnosis of myocardial injury of hand-foot -mouth disease and monitoring are critical to preventing disease from being worse. The combined CRP, heart kinase and hs-cTnT detection are of clinical significance in the prevention of myocardial injury of hand-foot-mouth disease.
出处
《实用临床医药杂志》
CAS
2013年第15期159-161,共3页
Journal of Clinical Medicine in Practice
关键词
C反应蛋白
心肌酶
高敏肌钙蛋白T
手足口病
心肌损伤
C- reactive protein, heart kinase, high- sensitivity troponin T, hand- foot- mouth disease, myocardial injury
