摘要
目的 考察川芎、当归与四物汤中其它两味药组合构成的 12种样本药物中阿魏酸含量的变化。方法 反相高效液相色谱法进行测定。结果 当归、川芎单味药阿魏酸煎出量分别为 0 .5 18,1.2 15mg·g- 1 ;加其它药味合煎后 ,阿魏酸煎出量为 0 .375～ 1.76 1mg·g- 1 。结论 川芎与当归合煎 ,阿魏酸的煎出量有一定的加合性 ;加入地黄或白芍后 ,阿魏酸煎出量降低 ;
OBJECTIVE To study the contents of the effective component ferulic acid in Siwutang and in other decoctions composed of one or more ingredients of Siwutang.METHODS The contents of ferulic acid were determined by reversed phase high performance liquid chromatography.RESULTS The ferulic acid contents in the decoction of angelica sinensis and the decoction of ligusticum chuanxiong were 0.518 mg·g -1 and 1.215 mg·g -1 ,respectively;they varied from 0.375 mg·g -1 to 1.761 mg·g -1 among Siwutang and the decoctions composed of two or three ingredients.CONCLUSION The content of ferulic acid in the decoction composed of angelica sinensis and ligusticum chuanxiong was the sum of that in the decoction of either of them;the contents of that decreasd in the decoctions combined with paeonia lactiflora and/or rehmannia glutinosa;the content of ferulic acid in Siwutang appeared to be moderate among all the relative decoctions.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2000年第11期767-768,共2页
Chinese Pharmaceutical Journal
基金
国家自然科学基金资助项目!(396 70 86 7)
