摘要
目的 :探讨乳腺肿瘤细针穿刺细胞学涂片进行雌激素、孕激素检测 ,作为内分泌治疗和预后的评估指标。方法 :用免疫组化方法在细针穿刺新鲜涂片检测乳腺良恶性肿瘤中 ER、PR的表达。结果 :2 2 6例乳腺肿块标记成功率为 88.0 5 % (199/2 2 6 ) ,ER/ PR阳性率为 41.2 1% (82 / 199)。其中 ER、PR的阳性表达为 :乳腺小叶增生 37.6 9% (49/ 130 ) ,纤维腺瘤 48.6 5 %(18/ 37) ,乳腺癌 46 .87% (15 / 32 )。结论 :细针穿刺细胞学 ER/ PR标记可作为一种临床常规检测方法之一。
Objective:Detecetion of ER and PR in fine needle aspiration tissues from breast neoplasms and breast cancer It may serve as an auxiliary indicators for endocrine treatment and prognosis Methods:Immunohistochemical staining(S P method)was used to detect specimens of breast meoplasms with FNA Results:Positive rate of ER and PR was 41 21%(82/199)in 226 specimens of breast neoplasms,37 69%(49/130)in breast lobular hyperplasia,48 65%(18/37)in fibroadenoma,46 87%(15/32)in breast cancer Conclusion:The result show fine needle aspiration tumor tissues from breast were detected for ER and PR,which can be used clinical routine examinations
出处
《广西医科大学学报》
CAS
2000年第4期560-562,共3页
Journal of Guangxi Medical University
基金
桂林市科委计划课题! ( NO:990 3 0 4)
关键词
乳腺肿瘤
细胞学
雌激素受体
孕激素受体
breast neoplasms
fine needle aspiration biopsy
estrogen receptor
progesterone receptor
immunohistochenistry
