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帕金森病的中医证型分布和用药规律探析 被引量:34

TCM syndrome distribution and rule of medication in Parkinson's disease
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摘要 目的通过文献分析,总结近年来有关帕金森病的中医辨证分型及处方用药研究概况,探寻其辨证论治规律。方法收集1998~2011年《万方数据库知识服务平台》收录的有关帕金森病中医证型和方药研究的相关文献,归纳统计主要证型和常用药物。结果①帕金森病中医证型10个,其中肝肾亏虚(18.1%)、气血不足(15.4%)、气血瘀滞(14.3%)、肾精不足(13.5%)、阴虚动风(11.6%)等5种证型最为常见,占总频次的72.9%。②归纳出15个病因病机要素,实证以痰、瘀、风为主,虚证以肾虚及气血两虚为主。③处方39首,常用方剂有大定风珠、导痰汤、天麻钩藤饮、大补阴丸、人参养荣汤等。④用药110种,按功能归为15类,补益药为第1位,活血药、安神药次之,此3类使用频次共占60.5%,再次为开窍药、化痰药等。结论帕金森病以心、肝、脾、肾四脏虚为本,以风、火、痰、瘀为标;临证可从肝、从肾、从风、从痰、从瘀论治。 Objective On the basis of literature research, this paper summarizes the TCM syndrome distribution and rule of medication in treating Parkinson' s disease in recent years, and aims to explore the rule of syndrome differentiation in TCM. Methods The papers on TCM syndrome and medication in Parkinson' s disease from 1998 to 2011 in wanfang database were collected. The syndromes and medicine in common use were collected. Results (~)Ten syndromes of Parkinson disease were collected, and 5 of them were in most common syndromes: deficiency of liver and kidney ( 18. 1% ), deficiency of qi and blood (15.4%), stagnation of qi and blood (14.3%), deficiency of kidney essence (13.5%), yin asthenia generating wind (11.6%). The total frequency is 72.9%. (~)Fifty pathogenic factors were collected, the sthenia syndromes are phlegm, blood stasis, wind; astherlia syndromes are kidney deficiency and deficiency of qi and blood mainly. (~)Thirty-nine prescriptions including "Dadingfeng Pill", "Daotan Decoction", "Tianma Gouteng Drink", "Dabuyin Pill", "Renshen Yangrong Decoction", ect. in common use. (~)One hundred and ten medicines were divided into 15 categories: first was tonifying and replenishing medicine; the second were blood-activating medicine and tranquillizing medicine. The frequency of the three medicines was 60.5%. Others were orifice-opening medicine and phlegm-transforming medicine. Conclusion The pathogenesis of the Parkinson' s disease is asthenia in the r^ot and sthenia in the branch. The deficiency of heart, liver, spleen and kidney are the root and wind, fire, phlegm and blood stasis are the branch. Parkinson' s disease can be treated from liver, kidney, wind, phlegm and blood stasis.
作者 顾超 袁灿兴
出处 《上海中医药杂志》 2013年第7期12-14,共3页 Shanghai Journal of Traditional Chinese Medicine
关键词 帕金森病 证型 方药 文献研究 Parkinson' s disease Chinese medical syndrome herb and prescription literature research
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参考文献5

  • 1Guttman M, Kish SJ, Frukawa Y. Current concepts in the diagnosis and management of Parkinson' s disease [ J ]. CMAJ, 2003, 168 ( 3 ) : 293-3011.
  • 2Rao SS, I-Iofmann LA, Shakil A. Parkinson' s disease:diagnosis and treatment[ J ]. Am Fam Physician ,2006,74 ( 12 ) :2046-2054.
  • 3陈彪,邹海强.帕金森病分子生物学和临床研究进展[J].中华神经科杂志,2002,35(1):2-4. 被引量:15
  • 4朱文峰.中医诊断学[M].上海:上海科学技术出版社,1999.
  • 5雷载权.中药学[M].上海:上海科学技术出版社,1999.150,277~278.

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