摘要
探讨彩色多普勒超声在乳腺癌新辅助化疗疗效评估中的价值。资料与方法:53例患者共57个肿块经超声引导下粗针穿刺活检确诊为浸润性乳腺癌且经临床评估需行新辅助化疗,在新辅助化疗前1周内及化疗后手术前行彩色多普勒超声检查,分析肿瘤大小、血流分布、血流阻力指数,根据RECIST指南,将患者分为有效组(CR组、PR组)及无效组(SD组、PD组),并与术后病理结果对比。结果:CR组共5例,由于肿块完全消失,化疗后血流消失;PR组中,新辅助化疗前后病灶RI值及血流分级变化均具有显著统计学意义(P<0.01),病灶前后PSV差异无统计学意义;无效组(SD组+PD组)中,新辅助化疗前后病灶内PSV、RI值及血流分级变化均无统计学意义。结论:彩色多普勒超声通过检测病灶大小及血流参数,可客观地评价乳腺癌新辅助化疗疗效,具有良好的临床价值。
Objective： To assess the value of color Doppler ultrasound（CDU） in evaluating the response of breast cancer to neoadjuvant chemotherapy （NAC）. Materials and Methods： This study included 53 patients with 57 breast cancer who were treated with NAC between January 2009 and June 2012. All patients were evaluated by CDU before and after NAC. The tu- mor sizes, peak systolic velocity （PSV）, distribution of blood flow and RI index were observed. All patients were divided into effective group （CR＋PR group） and ineffective group （SD＋PD group）. Results： Five patients were CR; In PR group, after NAC, resistive index（RI） and distribution of blood flow decreased（P〈O.O1）, but PSV did not change; In the ineffective group, PSV, RI and distribution of blood flow did not change（P〉0.05）. Conclusion： CDU is an effective method for evaluating the response of breast cancer to NAC.
出处
《中国临床医学影像杂志》
CAS
2013年第8期548-550,共3页
Journal of China Clinic Medical Imaging
关键词
乳腺肿瘤
超声检查
多普勒
彩色
Breast neoplasms
Ultrasonography, Doppler, color
