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补肾壮骨中药对去势雌性大鼠骨丢失的影响 被引量:4

Influences of Kidney_Reinforcing and Bone_Strengthening Chinese Herbal Medicine on the Bone Loss in Ovariectomized Rats
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摘要 为探讨补肾壮骨中药 (由淫羊藿、鹿角胶、龟板胶、骨碎补、巴戟天、淮山药、山茱萸、生地、肉桂等组成 )对骨质疏松症患者骨形成的促进作用及骨丢失的抑制作用 ,将 4 0只雌性大鼠随机分为假手术组、去势组、去势 +中药组、去势 +密钙息组 ,应用单光子骨密度仪测各组实验大鼠的左胫骨、右股骨、第 3腰椎体骨密度。结果表明 ,去势 +中药组骨密度较去势组上升 (P <0 .0 5) ,接近于假手术组 (P >0 .0 5)。提示 :补肾壮骨中药可以一定程度减少骨丢失 ,提高骨密度 ,对防治妇女绝经后骨质疏松症有效。 To explore the effect of kidney_reinforcing and bone_strengthening Chinese herbal medicine on the bone loss in ovariectomized rats, the bone mineral density (BMD)in left tibia, right femur and the third lumbar vertebrae was measured by single photon bone densitometry. Forty rats were allocated to four groups: Group Ⅰ(treated with imitative ovariectomy), Group Ⅱ(treated with ovariectomy), Group Ⅲ (treated with ovariectomy and Chinese herbal medicine) and Group Ⅳ(treated with western medicine).The results showed that BMD was increased in Group Ⅲ (P< 0.05 , compared with Group Ⅳ) and was similar to that in Group Ⅰ(P> 0.05 ). It is indicated that kidney_reinforcing and bone_strengthening Chinese herbal medicine can inhibit the bone loss to some extent and exert an effect on postmenopausal osteoporosis.
出处 《广州中医药大学学报》 CAS 2000年第3期233-234,共2页 Journal of Guangzhou University of Traditional Chinese Medicine
基金 广东省中医药管理局科研课题! (编号 :9731 8)
关键词 补肾药 绝经后骨质疏松 骨密度 中医药疗法 OSTEOPOROSIS, POSTMENOPAUSAL/TCD ther. KIDNEY_REINFORCING DRUGS/ther.use BONE DENSITY/drug eff.
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