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围产期孕妇泌尿生殖道无乳链球菌耐药性分析及临床意义 被引量:27

Analysis and clinical significance of drug resistance of Group B Streptococcus from pregnant women with perinatal genitourinary tract infection
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摘要 目的了解围产期孕妇泌尿生殖道无乳链球菌感染及耐药分布为临床合理用药提供依据,并提出预防措施,以引起临床重视。方法对门诊、住院围产期孕妇送检的泌尿生殖道标本进行培养鉴定,并对分离的无乳链球菌进行药敏试验,并用WHONET 5.5软件分析。结果 260株无乳链球菌药敏结果显示,对万古霉素、利奈唑胺、青霉素和头孢曲松的耐药率最低,对红霉素、克林霉素、左氧氟沙星的耐药率较高,分别为61.5%、57%和49.3%。结论临床医生应重视对围产期孕妇无乳链球菌的检测,实验室应准确报告无乳链球菌药敏结果,对临床合理用药治疗无乳链球菌感染具有重要指导意义并可预防其危害性。 Objective To understand the distribution of perinatal genitourinary tract infection of group B Streptococcus (GBS) in pregnant women and drug resistance, and provide basis for clinical treatment and prevention. Methods Specimens from the genitourinary tracts of perinatal outpatients and inpatients were cultured for bacterium identification; GBS was isolated and their sensitivity to antibiotics was determined. The data was analyzed by WHONET 5.5. Results A total of 260 strains of (; BS were detected ; their resistances to Van- comycin, Linezolid, Penicillin and Ceftriaxone were the lower, while the resistances to Eryflmm/ycin (61.5%) , Clindamycin (57%) and Levofloxacin (49.3%) were higher. Conclusion Clinicians should pay attention to GBS detection in perinatal women with genitou- rinary tract infection. Laboratory should report accurately the results of GBS drug sensitivity tests, which has an important guiding signifi- cance for the rational use of drugs in the treatment and prevention of GBS infection.
出处 《中国微生态学杂志》 CAS CSCD 2013年第8期966-968,共3页 Chinese Journal of Microecology
关键词 无乳链球菌 抗菌药物 耐药性 Streptococcus agalactiae Antibiotics Drug resistance
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