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抗N-甲基-D天冬氨酸受体脑炎1例报告并文献复习 被引量：5

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摘要 目的探讨抗N-甲基-D天冬氨酸受体脑炎(N-methyl-D-aspartate receptpr,NMDAR)的临床特点及诊治。方法回顾性分析1例经临床确诊的抗NMDAR脑炎患者的临床资料,并结合文献进行分析。结果主要临床特征为精神行为异常、癫及通气功能障碍,腹部B超发现畸胎瘤,脑脊液抗NMDAR抗体阳性,早期免疫治疗有效。结论抗NMDAR脑炎的临床表现复杂多样,不易识别,脑脊液抗NMDA抗体检测有助于早期诊断与治疗。
作者 吴勇 陈秀 谭华 李小刚
机构地区 泸州医学院附属医院神经内科
出处 《中国实用神经疾病杂志》 2013年第3期81-82,共2页 Chinese Journal of Practical Nervous Diseases
关键词 抗N-甲基-D天冬氨酸受体脑炎 畸胎瘤 通气功能障碍
分类号 R512.3 [医药卫生—内科学]
  • 相关文献

参考文献7

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  • 4Dalmau J,Lancaster E,Martinez-Hernande E,et al.Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis[J].Lancet Neurol,2011,10:63-74.
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二级参考文献10

  • 1Dalmau J,Gleichman AJ,Hughes EG,et al.Anti-NMDA-receptor encephalitis:case series and analysis of the effects of antibodies.Lancet Neurol,2008,7:1091-1098.
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  • 10周盛年,付秀鑫,刘艺鸣,曹丽丽,王波,李建军,李远,高艳景,宫晓平.畸胎瘤相关性副肿瘤边缘叶性脑炎一例[J].中华神经科杂志,2009,42(10):686-688. 被引量：10

共引文献110

同被引文献50

  • 1刘娟丽,王莉,杨春晓.抗NMDA受体脑炎新进展[J].中风与神经疾病杂志,2012,29(2):190-192. 被引量：18
  • 2Vitaliani R,Mason W,Anees B,et al.Paraneoplastic encephalitis,psychiatric symptoms,and hypoventilation in ovarian teratoma[J].Ann Neurol,2005,58:594-604.
  • 3Dalmau J,Tfizfin E,Wu HY,et al.Paraneoplastic anti-N-Methyl-Daspartate receptor encephalitis associated with ovarian teratoma[J].Ann Neurol,2007,61(1):25-36.
  • 4Granerod J,Ambrose HE,Davies NW,et al.Causes of encephalitis and differences in their clinical presentations in England:a multicenter,population-based prospective study[J].Lancet Infect Dis,2010,10(12):835-844.
  • 5Dalmau J,Lancaster E,Martinez-Hernandez E,et al.Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis[J].Lancet Neurol,2011,10(1):63-74.
  • 6Lizuka T,Sakai F.Anti-NMDA receptor encephalitis in Japan:longterm outcome without tumor removal[J].Neurology,2008,70(7):504-511.
  • 7Dalmau J,Gleichman AJ.Anti-NMDA-receptor encephalitis:case series and analysis of the effects of antibodies[J].Lancet Neurol,2008,7(12):1091-1098.
  • 8Ishiura H,Matsuda S.Response of anti-NMDA receptor encephalitis without tumor to immunotherapy including rituximab[J].Neurology,2008,71(23):1921-1923.
  • 9Poloni C,Korff CM,Ricotti V,et al.Severe childhood encephalopathy with dyskinesia and prolonged cognitive disturbances:evidence for anti-N-methyl-D-aspartate receptor encephalitis[J].Dev Med Child Neurol,2010,52:78-82.
  • 10Hung TY,Foo NH,Lai MC.Anti-N-methyl-D-aspartate receptor encephalitis[J].Pediatr Neonatol,2011,52:361-364.

引证文献5

二级引证文献23

中国实用神经疾病杂志
2013年 第3期

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