摘要
目的:探讨使用孟鲁司特钠治疗小儿咳嗽变异性哮喘的临床效果。方法:选取小儿咳嗽变异性哮喘患者140例,随机分为2组。其中对照组67例,观察组73例,使其有可比性。2组患者均给予止咳和氨茶碱治疗,对照组患者同时给予酮替芬片口服,观察组患者同时给予孟鲁司特钠口服。对2组患者治疗效果、治疗时间和费用以及复发情况进行评价。结果:观察组患者临床控制率和有效率均明显高于对照组;症状缓解和咳嗽消失时间分别为均明显短于对照组;不良反应发生率和复发率均明显低于对照组;平均复发时间明显晚于对照组。上述比较2组差异有统计学意义(P<0.05)。2组患者住院费用差别不大(P>0.05)。结论:对小儿咳嗽变异性哮喘息儿实施孟鲁司特钠治疗具有起效快、效果确切、不良反应少、不易复发等优点,是一种安全而有效的治疗手段,可以作为常规用药进行推广。
Objective： To explore the clinical significance of montelukast for cough variant asthma in children. Methods： 140 children with confirmed CVA were divided into control group and observation group. The patients in control group were treated with Ketotifen and the patients in observation group were treated with montelukast. Results： The clinical significance of the patients in observation group were better than control group; the remission time of symptoms was shorter; the rate of side effects and relapse were lower; the time to recurrence was later. There was a significant difference between the two groups （ P 〈 0.05 ）. There was little difference of the two groups of patients with hospital costs（ P 〉 0.05 ）. Conclusion：Children with cough variant asthma with the implementation of Montelukast used for chil- dren with cough variant asthma might be safe and effective,it could be used as conventional medication.
出处
《中国伤残医学》
2013年第8期74-75,共2页
Chinese Journal of Trauma and Disability Medicine
