摘要
目的：评价308nm准分子光联合吡美莫司乳膏治疗白癜风的疗效和安全性。方法：将100例白癜风患者随机分为2组。治疗组50例，采用308rim准分子光（2次／w）联合1％吡美莫司乳膏（2次／d）治疗。对照组50例，单纯应用1％吡美莫司乳膏（2次／d）治疗。2组均连续治疗12—24周，进行临床疗效和不良反应评价。结果：治疗组有效率为94．0％，对照组为50．0％。治疗组和对照组比较，有效率差异有统计学意义（P〈0．05）。2组患者均未出现严重不良反应。结论：308nm准分子光联合吡美莫司乳膏治疗白癜风疗效确切，安全性好，具有临床实际应用价值。
Objective： To evaluate the combination therapy efficacy and safety of 308rim excimer laser and Pimecrilimus Cream used in vilitigo treatment. Methods： 100 vilitigo patients were randomly divided into two groups. 50 patients in the treatment group received the combination therapy of 308nm excimer laser （ twice per week） and 1% Pimecrilimus Cream （ twice per day）, while the 50 patients in the control group only received the treatment of 1% Pimecrilimus Cream （twice per day）. After a continuous treatment for 12 to 24 weeks,the efficacies and adverse reactions were observed and evaluated respectively. Results： The effective rate of the treatment group was 94.0% and that of the control group was 50.0%. The difference was statistically significant （ P 〈 0.05）. Both of the two groups of patients did not meet serious adverse reactions. Conclusion： The combination therapy of 308rim excimer laser and Pimecrilimus Cream might be an effective and safe option for clinical application used in OLP treatment.
出处
《中国伤残医学》
2013年第8期76-77,共2页
Chinese Journal of Trauma and Disability Medicine
