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人类棕色脂肪的分布、影响因素及生理学作用 被引量：6

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摘要 人体内存在两种功能性脂肪组织：白色脂肪组织（whiteadiposetissue．WAT）和棕色脂肪组织（brownadiposetissue，BAT），共同维持机体能量代谢平衡。WAT是一种储能组织，通过分泌细胞因子和激素调节能量代谢。人体内WAT过度堆积可引起肥胖及肥胖相关疾病。BAT是一种耗能组织，参与非寒颤性产热和食物诱导性产热，
作者 魏丹 徐志鹏 薛耀明
机构地区 南方医科大学南方医院内分泌代谢科 第二军医大学附属长海医院泌尿外科
出处 《实用医学杂志》 CAS 北大核心 2013年第17期2918-2920,共3页 The Journal of Practical Medicine
关键词 棕色脂肪组织 生理学作用 影响因素 肥胖相关疾病 人类 白色脂肪组织 分泌细胞因子 能量代谢
分类号 R33 [医药卫生—人体生理学]
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参考文献18

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同被引文献51

  • 1王光亚,张素芬.脂联素与2型糖尿病及其大血管病变[J].国外医学（内分泌学分册）,2005,25(B04):39-41. 被引量：6
  • 2Manieri M, Murano I, Fianchini A, et al. Morphological and immunohis- tochemical features of brown adipocytes and preadipocytes in a case of human hibemoma [ J ]. Nutr Metab Cardiovasc Dis, 2010,20 ( 8 ) : 567 - 574.
  • 3Cypess AM, Lehman S, Williams G, et al. Identification and importance of brown adipose tissue in adult humans[ J]. N Engl J Med ,2009,360 (15) :1509 -1517.
  • 4Virtanen KA, Lidell ME, Orava J, et al. Functional brown adipose tissue in healthy adults[ J]. N Engl J Med,2009,360( 15 ) : 1518 - 1525.
  • 5Astrup A, Bulow J, Madsen J, et al. Contribution of BAT and skeletal muscle to thermogenesis induced by ephedrine in man [ J ]. Am J Physiol,1985,248(5 Pt 1) :E507 -515.
  • 6Van Marken Lichtenbelt WD, Vanhommefig JW, Smulders NM, et al. Cold-activated brown adipose tissue in healthy men [ J ]. N Engl J Med, 2009,360( 15 ) : 1500 - 1508.
  • 7Yoneshiro T, Aita S, Matsushita M, et al. Age-related decrease in cold- activated brown adipose tissue and accumulation of body fat in healthy humans[J]. Obesity (Silver Spring) ,2011,19(9) :1755 -1760.
  • 8Saito M, Okamatsu-Ogura Y, Matsushita MA, et al. High incidence of metabolically active brown adipose tissue in healthy adult humans effects of cold exposure and adiposity [ J ]. Diabetes, 2009,58 ( 7 ) : 1526 - 1531.
  • 9Tseng YH, Kokkotou E, Schulz TJ, et al. New role of hone morphoge- netic protein 7 in brown adipogenesis and energy expenditure [ J ]. Nature ,2008,454 (7207) : 1000 - 1004.
  • 10Cederberg A, Gronning LM, Ahren B, et al. FOXC2 is a winged helix gene that counteracts obesity, hypertriglyeeridemia and diet induced in- sulin resistance [ J ]. Cell,2001,106 (5) :563 - 573.

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实用医学杂志
2013年 第17期

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