摘要
目的探讨结直肠癌伴同时性肝转移的治疗方法。方法回顾性分析78例结直肠癌伴同时性肝转移患者的临床资料,对手术方式及结果进行讨论。结果 52例手术切除原发病灶并同期行肝转移病灶切除;26例在结直肠癌原发灶切除术后2～6个月行延期肝转移灶切除,术后1、3、5年生存率同期组分别为75.0%、40.4%、35.0%;延期组分别为73.1%、34.6%、23.1%,两组均无围手术期死亡病例。结论在结直肠癌原发病灶及肝转移灶均可切除的情况下,应争取行同期手术切除;若因合并肠梗阻等情况不宜同期切除者,可在原发灶切除后行肝转移病灶介入或局部物理、化学治疗,再争取行延期切除,或考虑行肝脏移植术。
Objective To investigate the treatment method of colorectal cancer with synchronous liver metastasis. Meth- ods Clinical data of 78 colorectal cancer patients with synchronous liver metastasis were analyzed retrospectively, and the fac- tors such as the surgical methods, and follow-up result were discussed. Results Fifty-two cases （group synchronization） un derwent operation of resecting the primary lesion and liver metastasis during the same period; 26 cases （group delay） under- went operation of resecting liver metastasis after resection of primary lesion 2-6 months delayed. The 1-, 2-and 3-year overall survival rates in group synchronization were 75.0%, 40. 4%, and 35.0%, in group delay were 73. 1%, 34.6% and 23. 1%. Mortality rate was 0. Conclusion It should be strived for surgical ablation in coloreetal cancer with synchronous liver metasta sis. If combined with intestinal obstruction etc, it can be strived for extended resection or hepatic transplantation after embolism chemotherapy of hepatic artery interventional or local physical, chemical treatmont.
出处
《福建医药杂志》
CAS
2013年第4期25-27,共3页
Fujian Medical Journal
关键词
结直肠癌
肝转移
colorectal cancer
synchronous liver metastasis
