摘要
目的了解石家庄市大学生献血者丙氨酸氨基转移酶(ALT)不合格率及其影响因素。方法采用全自动生化分析仪检测2011年初筛合格的40 257份大学生献血者血液标本中ALT活力,对ALT不合格大学生献血者进行随访,调查其影响因素。结果 40 257份大学生献血者中ALT不合格608名,不合格率较低(1.51%),与同期献血的其他献血人群比较,差异有统计学意义(P<0.05)。男性不合格率高于女性,差异有统计学意义(P<0.05);第3季度ALT不合格率较高,与其他季度相比,差异具有统计学意义(P<0.05);随着献血次数的增加,ALT不合格率降低(χ2=49.05,P<0.01)。ALT不合格多为单项ALT活力增高,且97.9%为非病理性原因引起。结论大学生献血者血中ALT不合格率低于其他人群献血者,应减少由非病理因素引起的ALT不合格而导致的血液报废率。
[Objective]To understand the unqualified rate of alanine aminotransferase （ALT） and its influencing factors among blood donors from college students in Shijianzhuang City. [ Methods ] The blood samples of 40 257 blood donors from college students in 2011 were examined for ALT activity by automatic biochemical analyzer, and influencing factors of unqualified ALT activity were investigated through the follow-up survey. [ Results ] 608 of 40 257 blood donors from college students were unqualified in ALT activity, the unqualified rate was 1.51% , and the difference in unqualified rate between college student blood donors and other donation groups was significant （ P 〈 0. 05 ）. The unqualified rate of ALT activity in male students was significantly higher than that in female students （ P 〈 0.05 ）. The unqualified rate of ALT activity in the third quarter was higher than that in the other quarters, which showed a statistically significant difference （P 〈 0.05 }. With the increasing number of blood donation, the unqualified rate of ALT activity decreased （ X2 = 49.05, P 〈 0.01 ）. Most of students with unqualified ALT activity had increasing of single ALT index, and 97.9% were caused by non-pathological causes. [ Conclusion] The unqualified rate of ALT activity among blood donors from college students is lower than that among other donation groups. It is necessary to decrease blood rejection rate caused by unqualified ALT activity with non-pathological causes.
出处
《职业与健康》
CAS
2013年第17期2185-2186,2191,共3页
Occupation and Health
关键词
献血者
丙氨酸氨基转移酶
影响因素
Blood donors
Alanine aminotransferase （ ALT）
Influencing factors
