摘要
目的:探讨首发、复发及双相抑郁患者精神症状的差异。方法:对首次抑郁发作患者(首发组,24例)、复发性抑郁症患者(复发组,57例)及双相抑郁患者(双相组,25例)进行汉密尔顿抑郁评定量表(HAMD)、汉密尔顿焦虑评定量表(HAMA)、杨氏躁狂评定量表(YMRS)以及阳性和阴性症状评定量表(PANSS)评定和比较。结果:HAMD、HAMA评分在3组间差异无统计学意义;YMRS评分3组间差异有统计学意义(F=5.2,P=0.007);双相组(6.6±9.0)显著高于首发组(2.8±3.4)和复发组(2.2±3.2)(q=3.86,q=4.40;P均<0.05)。双相组HAMD中的躯体焦虑因子分、体重因子分均显著低于复发组(P<0.05或P<0.01);双相组精神病理学症状评分如意志活动、愤怒、幻觉、易激惹、激越、思维联想加快、破坏或攻击行为、活动增加显著高于首发组及复发组(P<0.05或P<0.01)。结论:双相障碍患者抑郁发作时可出现与躁狂相关精神症状。
Objective：To explore the difference in mental symptoms among depressive patients with first episode,recurrent and bipolar episode.Method：The evaluations of Hamilton depression scale（HAMD）,Hamilton anxiety scale（HAMA）,Young mania rating scale （YMRS） and positive and negative symptoms rating scale （PANSS） were preformed in 24 patients with first episode （first episode group）,57 patients with recurrence depression （recurrence group） and 24 patients with bipolar depression （bipolar group）.The results were compared among the three groups.Results：The scores of HAMD,HAMA among the three groups were no significant difference,but score of YMRS among the three groups were significantly different （F=5.2,P=0.007）.The score of YMRS in bipolar group （6.6±9.0） was significantly higher than first episode group （2.8±3.4） and recurrence group （2.2±3.2）（q=3.86,q=4.40;all P0.05）.The scors of somatic anxiety factor and weight factor of HAMD in bipolar group were significantly lower than those in recurrence group （P0.05 or P0.01）;the scores of psychiatric symptoms such as the will of the activities,anger,hallucinations,bowel,agitation,thinking racing,accelerated destruction or aggressive behavior,increased activity were higher significantly than those in first episode group and recurrence group （P0.05 or P0.01）.Conclusion：The patients with bipolar disorder can appear mental symptoms associated with mania when depressive episodes.
出处
《临床精神医学杂志》
2013年第4期238-240,共3页
Journal of Clinical Psychiatry
关键词
抑郁发作
首发抑郁症
复发性抑郁
双相抑郁
精神症状学
depressive episode
first depression
recurrent depression
bipolar depression
mental symptoms
