摘要
目的探讨适形放疗联合化疗治疗局限期小细胞肺癌的临床疗效。方法选取在我院接受治疗的局限期小细胞肺癌患者共63例,随机分为观察组33例,对照组30例。观察组为放、化疗同步疗法。对照组为放、化疗序贯疗法。结果治疗后,观察组与对照组的治疗总有效率分别为93.9%、83.3%,比较发现,观察组的总有效率明显高于对照组(P<0.05)。随访两年中,观察组与对照组1、2年的生存率分别为81.8%(27/33)、70.0%(21/30)与72.7%(24/33)、36.7(11/30),差异具有统计学意义(P<0.05)。治疗过程中,观察组患者出现毒副反应的情况略高于对照组,但差异不具有统计学意义(P>0.05)。结论适形放疗联合化疗治疗局限期小细胞肺癌疗效显著,安全可靠。
Objective To investigate the clinical effect of conformal radiotherapy combined with chemotherapy in the treatment of patients with limited stage small cell lung cancer. Methods 63 patients with limited stage small cell lung cancer were randnmly divided into the observation group （33 cases） and the control group （30 cases）. The observation group was treated with chemotherapy concurrent therapy, and the control group was treated with chemotherapy sequential therapy. Results After the treatment, the total effective rate was 93.9% and 83.3% in the observation group and the control group respectively （P 〈 0. 05）. The survival rates of 1-year and 2-year tbl- low-up were 81.8% （27/33）, 70% （21/30） and 72.7% （24/33）, 36.7 （11/30） respectively in the observation group and in the control group. During the treatment course, the incidence of adverse reactions was slightly higher in the observation group than in the con- tml group, but without significant difference （P 〉 0. 05）. Conclusion The curative effect of radiotherapy combined with chemotherapy in the treatment of patients with limited stage small cell lung cancer is remarkable, safe and reliable, and it is worthy of popularization and application.
出处
《临床肺科杂志》
2013年第10期1872-1873,共2页
Journal of Clinical Pulmonary Medicine
关键词
三维适形放疗
局限期
小细胞肺癌
疗效
three-dimensional conformal radiotherapy
limited stage small cell lung cancer
curative effect
