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动脉粥样硬化的胎儿起源及机制研究 被引量：1

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摘要 动脉粥样硬化（AS）是以血管壁脂质积聚及炎性细胞浸润为特征的常见血管性疾病。动脉壁内膜的粥样病灶在晚期可形成纤维脂质斑块，动脉壁增厚、纤维增生及钙化，从而使血管弹性减退、管腔变窄甚至阻塞，严重时合并血栓形成、AS斑块脱落，可造成重要的冠状血管或脑血管阻塞，而引起冠心病、脑中风等严重心脑血管疾病。
作者 胡淑伟 龚俊 喻红 汪晖
机构地区 武汉大学基础医学院药理学系 武汉大学基础医学院生物化学与分子生物学系
出处 《医学新知》 CAS 2013年第4期252-254,共3页 New Medicine
基金 国家自然科学基金重点和重大国际合作项目（编号：30830112：81220108026）
关键词 动脉粥样硬化 胎儿起源 表观遗传修饰 氧化应激 炎症 脂代谢
分类号 R543.5 [医药卫生—心血管疾病]
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医学新知
2013年 第4期

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