摘要
目的探讨联合应用CT灌注成像(CTP)和CT血管成像(CTA)技术对急性脑梗死的临床诊断价值。方法38例临床怀疑急性脑梗死的患者进行脑CTP联合头颈部CTA扫描检查,扫描结束后,采用CT灌注软件和血管软件进行评估。结果梗死区与对侧脑区相比,脑灌注量值、强化峰值、达峰时间(TTP)差异有统计学意义;脑血容量差异无统计学意义;相对脑灌注量、相对脑血容量呈下降趋势;梗死区TTP值显著延长。CTA显示:38例患者中8例患者(21%)病灶侧大血管大致正常;12例(32%)发现病灶侧大脑中动脉狭窄、闭塞;5例(13%)病灶侧大脑前动脉狭窄、闭塞;5例(13%)病灶侧大脑后动脉狭窄、闭塞;8例(21%)病灶侧颈内动脉狭窄、闭塞。结论 CTP及CTA联合一站式检查,体现出快捷、经济的特点,在观察急性脑梗死血液动力学改变时又能分析病变区供血动脉的情况,能为临床诊断和治疗提供更多病理、生理学信息。
Objective To study the clinical diagnosis value of the combination application of CT perfusion （CTP） and CT angiography （CTA） on acute cerebral infarction. Methods Thirty-eight patients suspected of acute cerebral infarction were examined with CTP and CTA. All the CTA data was send to 3D pestprocessing card for MIP, and VR reconstruction. Perfusion data were analyzed by CT peffusion package. Results Compared with contralateral brain regions, the value of perfusion, PE, and TTP were significantly different in the infarcted area. CBV value was not statistically different, r-perfusion, r-CBV decreased as well as TTP value significantly extended. Ipsilateral vascular was generally normal in 8 patients （21%）. Twelve eases （32%） had ipsilateral middle cerebral artery stenosis or occlusion. Each of 5 patients （13%） showed anterior or posterior cerebral artery lesions. The internal carotid artery stenosis or occlusion in 8 cases （21%）. Not found of intracranial aneurysms, vascular malformations and intracranial lesions in all 38 cases. Conclusion Combined application of CTP and CTA can finish examinations in the fast and economic way. Both the hemodynamics changing and the morphology of the vessels were demonst rated which providing omnidirectional pathophysiological information for clinical diagnosis and therapy.
出处
《实用医技杂志》
2013年第9期939-941,共3页
Journal of Practical Medical Techniques
关键词
体层摄影术
螺旋计算机
成像
三维
脑梗死
脑血管造影术
Tomography, spiral computed
Imaging, three-dimensional
Brain infarction
cerebral angiography
