摘要
目的了解肺癌肉瘤的临床、病理特点，探讨其可能的组织学来源及合理的治疗方式。方法：对12例肺癌肉瘤患者的临床资料进行回顾性分析。结果12例患者均行手术治疗，手术切除率、手术并发症发生率及手术死亡率分别为100．0％、16．7％和8．3％。光镜下表现为癌与肉瘤成分混合存在，癌的成分及肉瘤的成分多种多样。本组患者的术后5年生存率为33．3％，已证实死亡的5例患者除1例死于术后并发症外，其余均死于远处转移。结论：肺癌肉瘤是一种恶性程度并不高于一般肺癌的恶性肿瘤。手术切除是其首选的治疗手段。手术指征应包括Ⅲa期、部分Ⅲb期及Ⅳ期患者。其组织学来源除上皮来源外，不除外个别非上皮来源的可能。
Objective To evaluate the clinical and pathological characteristics and origin of pulmonary carcinoma and find reasonable mode of treatment． Methods The clinical materials of 12 patients with pulmonary carcinoma were retrospectively studied． Results All the 12 patients were treated with operation． The resectibility morbidity and 30－day mortality rates were 100．0％ 16．7％ and 8．3％ respectively． Microscopically the tumors were composed of both carcinomatous and sarcomatous elements． The carcinomatous elements and the sarcomatous elements were various． The postoperative 5－yr survival rate was 33．3％． In all the 5 died patients four died of distant metastasis only one died of operative complication． Conclusion Pulmonary carcinosarcoma is a malignant disease with lower malignancy than that of general lung cancer． Surgical resection is the first preferable treatment． The surgical indications should include the patients with stage 0ⅠⅡⅢa or even some Ⅲb or Ⅳ tumors． Its histological origins mostly are epithelial but occasionally may be non－epithelial．
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2000年第9期660-662,共3页
Chinese Journal of Clinical Oncology
基金
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关键词
肺癌肉瘤
病理特点
外科手术
诊断
Pulmonary neoplasm Carcinosarcoma Surgical treatment
