摘要
生存蛋白(survivin)具有调控细胞有丝分裂和抑制程序性细胞死亡的双重功能,可干扰细胞的增殖与程序性死亡,进而影响疾病的发生发展进程。近年来,生存蛋白与口腔疾病间的关系备受瞩目,本文就生存蛋白及其与口腔肿瘤、牙周病和唾液腺发育间的关系等研究进展作一综述。
Survivin, a member of the inhibitor of apoptosis protein family, functions as a regulator of mitosis and cell-death decisions. Snrvivin affects the initiation and progression of diseases by interfering with cell proliferation and apoptosis. In recent years, the relationship between survivin and oral diseases has attracted considerable research attention. This article focuses on the biological functions of survivin as well as relevant research progress in oral cancer, periodontal diseases, and salivary gland development.
出处
《国际口腔医学杂志》
CAS
2013年第5期674-677,共4页
International Journal of Stomatology
基金
国家自然科学基金资助项目(81070834
81271153)
