摘要
目的总结甲状腺髓样癌（medullary thyroid carcinoma，MTC）的临床病理特征及治疗方法。方法回顾性分析1995年1月至2010年2月福建医科大学省立临床医学院手术治疗的42例MTC临床资料。结果42例均手术治疗，经病理证实为MTC，颈部淋巴结经病理证实转移率为76．19％（32／42），中央区淋巴结转移率为61．90％（26／42）。术后中位随访时间102（1—502）个月，随访5年以上35例（83．33％），5年生存率为85．71％（30／35），死亡5例。结论MTC淋巴结转移率高，治疗应以根治性切除为原则，原发灶处理宜行甲状腺全切除，淋巴结清扫应力求彻底，至少行中央区淋巴结清扫。
Objective To explore the clinicopathologic characteristics and treatment of medullary thyroid carcinoma（ MTC ）. Methods The data of 42 cases of MTC admitted to Fujian Medical University Provincial Clinical College from Jan 1995 to Feb 2010 were retrospectively analyzed. Surgery was performed in all the 42 cases. All were proved to be MTC by pathology. Results Surgery was performed in all the 42 cases. All were proved to be MTC by pathology. The lymph node metastasis rate was 76. 19% （32/42）. The central lymph node metastasis rate was 61.90% （26/42）. All the 42 cases were followed up for 1 to 502 months with 102 months as the median. 35 cases（83.33% ）were followed up for more than 5 years and the 5-year overall survival rate was 85.71% （30/35）. Death occurred in 5 cases. Conclusions The lymph node metastasis rate of MTC is high. The treatment should be based on the principle of radical resection. Total thyroidectomy should be recommended to treat primary tumor. Lymph node dissection should be as thorough as possible. Central compartment neck dis- section should be done in all cases.
出处
《中华内分泌外科杂志》
CAS
2013年第4期275-277,共3页
Chinese Journal of Endocrine Surgery
关键词
甲状腺肿瘤
髓样癌
Thyroid neoplasms
Medullary carcinoma
