摘要
目的应用心率变异非线性分析评估慢性肾衰 (CRE)尿毒症患者的心脏自主神经功能损害情况。方法采用 2 4小时动态心电图对 2 8例CRF尿毒症病人和 5 4例健康人监测 ,以Poincare散点图进行心率变异性 (HRV)非线性分析 ,并与部分时域指标比较。结果尿毒症组Poincare散点图大多数呈鱼雷状 ,其定量指标VLI(98 2 9± 40 5 9)和VAI(0 46± 0 16 )明显低于对照组 (VLI:175 6 8± 42 77,VAI:0 75± 0 30 ) ,P <0 0 1,并与时域指标相关。结论HRV非线性分析可作为无创性定量评价尿毒症患者心脏自主神经功能的可靠方法 ,心脏自主神经功能受损可能是尿毒症患者发生心脏意外的危险信号。
Objective [WT5”BZ]To evaluate cardiovascular autonomic function in patients with end-stage renal failure with non-linear analysis.[WT5”HZ]Methods [WT5”BZ] 28 chronic uremia patients and 54 normal subjects were collected by 24-hour ambulatory electrocardiography for HRV,and the non-linear analysis of vector length index (VLI) and vector angle index (VAI) were done.[WT5”HZ]Results [WT5”BZ]Cometshaped poincare plot in control group was 90% (49/54),torpedo pattern in uremic group was 80% (22/28).Plot of uremic group was shorter and narrower than that of control group.The VLI in uremic group and control group were 98 29±40 59 and 175 68±42 77 respectively ( P <0 01).The VAI in uremic group and control group were 0 46±0 16 and 0 75±0 30 respecticely( P <0 01).Conclusion The end-stage renal disease experience autonomic dysfunctions that may be responsible for sudden cardiac death.The non-linear analysis of HRV was a non-invasive and quantitative method evaluating autonomic neuropahy.
出处
《贵州医药》
CAS
2000年第11期654-655,共2页
Guizhou Medical Journal
关键词
尿毒症
心率变异性
非线性分析
慢性肾衰
ANS
Uremia Heart rate variability Non-linear analysis Autonomic nervous systemt
