期刊文献+

非酒精性脂肪肝患者高危风险因素分析及护理对策 被引量:2

High risk factors and nursing strategies for patients with nonalcoholic fatty liver disease
原文传递
导出
摘要 目的 对非酒精性脂肪肝(NAFLD)患者高危风险因素进行分析并制定相应的护理对策.方法 对山东省日照市人民医院健康体检中心诊断的l 151例NAFLD患者和4 113名非NAFLD对照人群进行回顾性分析,采用二分类非条件Logistic回归分析,对NAFLD高危因素进行筛查.结果 NAFLD患者的高危风险因素分别为性别、超重或肥胖、高血糖、高血压、血脂紊乱、高胆固醇血症和高尿酸血症,男性NAFLD患者超重或肥胖(77.9%)、高血压(24.4%)、高血糖(40.2%)、血脂紊乱(58.6%)、高胆固醇血症(45.1%)和高尿酸血症(27.0%)的检出率均显著高于对照人群(38.1%,12.0%,26.3%,27.7%,33.5%,10.2%),两组比较差异有统计学意义(x2值分别为463.2,87.2,145.1,303.0,383.9,162.5;P <0.05);女性NAFLD患者相应病症的检出率也均高于对照人群(68.5%/21.7%,30.8%/6.4%,44.8%/14.4%,52.4%/17.9%,56.7%/27.2%,21.0%/5.9%),两组比较差异均有统计学意义(x2值分别为147.9,98.7,84.2,93.4,328.9,44.1;P<0.05).结论 护理人员更应关注NAFLD高危人群,通过生活方式或药物干预消除或减轻高危因素,以预防或延缓NAFLD的发生和发展. Objective To analyze the high risk factors and nursing strategies for patients with nonalcoholic fatty liver disease (NAFLD).Methods The medical checkup data of 5 264 people from medical centers for health examination were analyzed by binary Logistic regression analysis,who included 1 151 patients with NAFLD and 4 113 control peoples.Results The high risk factors of NAFLD included sex,overweight or obesity,hyperglycemia,hypertension,dyslipidemia,hypercholesterolemia and hyperuricemia.The detection rate of overweight or obesity,hyperglycemia,hypertension,dyslipidemia,hypercholesterolemia,hyperuricemia were significantly higher in NAFLD group than those in control group among male [77.9% vs 38.1%,24.4% vs 12.0%,40.2% vs 26.3%,58.6% vs 27.7%,45.1% vs 33.5%,27.0% vs 10.2%],as well as females [68.5% vs21.7%,30.8% vs6.4%,44.8% vs 14.4%,52.4% vs 17.9%,56.7% vs 27.2%,21.0% vs 5.9%],the difference were statistics significant (x2 =463.2,87.2,145.1,303.0,383.9,162.5 and 147.9,98.7,84.2,93.4,328.9,44.1,respoetively;P <0.05).Conclusions Nursing staff should pay more attention to high-risk population of NAFLD,and eliminate or reduce risk factors through the way of life or drugs intervention to prevent or delay the NAFLD occurrence and development.
作者 杨晖 陈慧
出处 《中华现代护理杂志》 2013年第23期2795-2798,共4页 Chinese Journal of Modern Nursing
关键词 护理 非酒精性脂肪肝 高危因素 Nursing Nonalcoholic fatty liver Risk factors
  • 相关文献

参考文献17

  • 1Fatty Liver and Alcoholic Liver Disease Study Group of the Chinese Liver Disease Association..非酒精性脂肪性肝病诊疗指南[J].中华肝脏病杂志,2006,14(3):161-163. 被引量:1513
  • 2Cheung O,Kapoor A,Pui P,et al.The impact of fat distribution on the severity of nonalcoholic fatty liver disease and metabolic syndrome.Hepatology,2007,46 (4):1091-1100.
  • 3Gastaldelli A,Kozakova M,Hφjlund K,et al.Fatty liver is associated with insulin resistance,risk of coronary heart disease,and early atherosclerosis in a large European population.Hepatology,2009,49 (5):1537-1544.
  • 4Lu H,Zeng L,Liang B,et al.High prevalence of coronary heart disease in type 2 diabetic patients with non-alcoholic fatty liver disease.Arch Med Res,2009,40(7):571-575.
  • 5Sung KC,Ryan MC,Wilson AM.The severity of nonalcoholic fatty liver disease is associated with increased cardiovascular risk in a large cohort of non-obese Asian subjects.Atherosclerosis,2009,203(2):581-586.
  • 6Matteoni CA,Younossi ZM,Gramlich T,et al.Nonalcoholic fatty liver disease:a spectrum of clinical and pathological severity.Gastroenterology,1999,116 (6):1413-1419.
  • 7Targher G,Bertolini L,Padovani R,et al.Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients.Diabetes Care,2007,30(5):1212-1218.
  • 8Dunn W,Xu R,Wingard DL,et al.Suspected nonalcoholic fatty liver disease and mortality risk in a population-based cohort study.Am J Gastroenterol,2008,103 (9):2263-2271.
  • 9范建高,蔡晓波.非酒精性脂肪性肝病促进动脉粥样硬化的发生[J].中国动脉硬化杂志,2008,16(1):1-3. 被引量:30
  • 10Caballería L,Pera G,Auladell MA,et al.Prevalence and factors associated with the presence of nonalcoholic fatty liver disease in an adult population in Spain.Eur J Gastroenterol Hepatol,2010,22 (1):24-32.

二级参考文献88

共引文献1710

同被引文献23

  • 1王丽华.36 例2 型糖尿病合并非酒精性脂肪肝患者临床观察及护理策略[J].临床护理,2010,11(12):45-46.
  • 2Kwon HK,Greenson JK,Conjeevaram HS,et al.Effect of life-time alcohol consumption on the histological severity of nonalcoholicfatty liver disease[J].Liver Int,2014,34(1):129-135.
  • 3Brea A,Puzo J.Non-alcoholic fatty liver disease and car-diovascular risk[J].Int J Cardiol,2013,167(4):1109-1117.
  • 4AravinthanA,ScarpiniC,TachtatzisP,et al.Hepatocytesenes-cence predicts progression in non -alcohol -related fattyliver disease[J].J Hepatol,2013,58(3):549-556.
  • 5Leung TM,Nieto N.CYP2E1 and oxidant stress in alcoholicand non-alcoholic fatty liver disease[J].J Hepatol,2013,58(2):395-398.
  • 6Stammberger HR, Kenney DW. Paranasal sinuses: anatomic ter- minology and nomenclature[J]. Ann Oto Rhi nol Laryngol,2011, 167 (suppl) :7 - 16.
  • 7Wormald PJ. The agger nasi cell: the key to understanding the a- natomy of the frontal recess[J]. Otolaryngol Head Neck Surg, 2011,12(9) :497 - 507.
  • 8Choi Bi, Lee H J, Han JK,et al. Detection of hypervascular nodular hepatocellur carcinomas: value of triphasic helical CT compared with iodized oil CT[J]. AJR,2010,157(2) :219 -224.
  • 9Khan MA,Combs CS, Brunt EM,et al. Positron emission tomo- graphy scanning in the evaluation of hepatocellular carcinoma[J]. Ann Nucl Med,2009,14(2) :121 - 126.
  • 10Tabit CE, Chung WB, Hamburg NM,et al. Endothelial dysfunc- tion in diabetes mellitus:molecular mechanisms and clinical impli- cations[J].Rev Endocr Metab Disord,2010,11(1):61 -74.

引证文献2

二级引证文献29

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部