摘要
目的追踪研究妊娠妇女甲状腺自身抗体和促甲状腺素水平变化,探讨其对预测流产的价值。方法选择2007年1月—2009年12月在该院产科门诊就诊,年龄24～36岁,无其他危险因素的250例单胎妊娠妇女,于妊娠20周内检测甲状腺自身抗体和促甲状腺素。结果 250例单胎妊娠妇女中,50例流产,200例持续妊娠,其中单纯自身抗体阳性32例,流产率56.2%,单纯TSH≥2.5 mIU·L-14例,流产率为25%,TSH≥2.5 mIU·L-1伴自身抗体阳性10例,流产率100%,TSH﹤2.5mIU·L-1伴自身抗体阴性194例,流产率为10.8%。结论甲状腺自身抗体和促甲状腺素是预测流产的重要指标,且甲状腺自身抗体预测流产价值更大。
Objective To track pregnancy women for study in thyroid autoantibodies and thyroid-stimulating hormone levels change,to explore their forecasting value on abortion. Methods We selected patients admitted from January 2007 to December 2009 in our hospi-tal, aged 24 to 36, without other risk factors, totally 250 cases of single pregnancy women, and detected their thyroid autoantibodies and thyroid stimulating hormone in 20 gestational weeks. Results Of 250 cases with single pregnancy women, abortion occurred in 50 cases, 200 cases continued to pregnancy, including pure autoantibody positive 32 cases, abortion rate being 56.2%. Pure TSH ≥2.5 mIU · L^-1 4 cases, the abortion rate was 25%. TSH/〉2.5 mIU · L^-1 with positive autoantibodies were found in 10 cases, abortion rate 100%. TSH 〈 2.5 mIU · L^-1 with autoantibody negative were found in 194 cases, abortion rate 10.8%. Conclusions Thyroid autoantibodies and thyroid stimulating hormone are important predictors of miscarriage, and thyroid autoantibodies prediction value is greater.
出处
《安徽医药》
CAS
2013年第9期1542-1543,共2页
Anhui Medical and Pharmaceutical Journal
关键词
甲状腺自身抗体
促甲状腺素
流产
血清甲状腺过氧化酶抗体
thyroid autoantibodies
thyroid stimulating hormone
abortion
serum levels of thyroid peroxidase antibodies
