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手术治疗亚急性甲状腺炎效果观察

Effect of operation in the treatment of subacute thyroiditis
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摘要 目的探讨亚急性甲状腺炎的外科治疗疗效。方法回顾性分析87例亚急性甲状腺炎患者的临床资料。依据患者治疗方法分为手术组39例、内科治疗组(保守组)48例。患者治疗结束后随访6个月,比较两组治疗结束后1周临床效果,比较两组治疗后6个月时的甲状腺功能。结果手术组甲状腺功能亢进(甲亢)发生率(33.33%)显著高于保守组(8.33%),差异有统计学意义(x^2=8.554,P=0.003)。手术组与保守组短期治疗有效率(89.74%与93.75%)差异无统计学意义(x^2=0.467,P=0.495)。两组患者治疗后6个月甲状腺功能正常率差异无统计学意义(x^2=4.947,P=0.084)。保守组随访中确诊3例为甲状腺癌伴甲亢。结论亚急性甲状腺炎的治疗方式应以内科治疗为主,但有一定的误诊率。对于顽固性亚急性甲状腺炎以及恶性肿瘤不能排除时,可选择手术方式治疗,但需全面评估手术的必要性。 Objective To explore the curative effects of operation in treatment of subacute thyroiditis. Methods The clinical data of 87 patients with subaeute thyroiditis were retrospectively analyzed. According to the treatment methods, 87 patients were divided into the operation group 39 cases and the medical treatment group( conser- vative group) 48 cases. Patients were followed up for 6 months after treatment. The clinical effeet 1 week after the end of treatment was compared between the two groups. The thyroid function at 6 months after the end of treatment was com- pared. Results The incidence rate of thyroid hyperfunction (hyperthyroidism) of the operation group was 33.33%, which was significantly higher than 8.33 % in conservative group, the difference was statistically significant ( x^2 = 8. 554, P = 0.003 ). The effective rate of short-term treatment of operation group and the conservative group was 89.74% and 93.75% ,the difference was not significant( x^2 = 0.467 ,P = 0. 495 ). After 6 months of treatment ,the normal rate of thy- roid function between the two groups had no statistically significant difference(x^2=4.947 ,P =0. 084). In the conserva- tive group ,3 cases were diagnosed as thyroid earcinoma complicated with hyperthyroidism. Conclusion For patients with refractory subaeute thyroiditis or cannot exclude malignant tumors, operation can achieve good effect and less com- plications.
作者 刘连仲
出处 《中国基层医药》 CAS 2013年第22期3418-3420,共3页 Chinese Journal of Primary Medicine and Pharmacy
关键词 甲状腺炎 亚急性 手术治疗 疗效 Thyroiditis, subacute Operation treatment Curative effect
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