摘要
目的:观察吸烟对类风湿关节炎患者的凝血与纤溶障碍的影响。方法:将123例类风湿关节炎患者分为吸烟组66例和非吸烟组57例,进行治疗前后的凝血与纤溶的研究,并设健康对照组50例。结果:两组类风湿关节炎患者治疗前与健康组比较,有不同程度的凝血与纤溶障碍(P<0.05)。治疗前吸烟组患者与非吸烟组比较,有明显的凝血与纤溶障碍(P<0.05)。经治疗非吸烟组比吸烟组症状好转(有效率88.2%),且凝血与纤溶障碍有明显改善,两组比较,差异有统计学意义(P<0.01)。结论:吸烟可加重类风湿关节炎患者凝血与纤溶障碍,对该病的治疗和预后有不良影响。
Objective：To observe the effects of smoking on blood coagulation and fibrinolysis impediment of patients with rheumatoid arthritis （ RA ） .Methods： 123 cases with RA were divided into the smoking group （ 66 cases ） and the non-smoking group （ 57 cases ） ,studying their blood coagulation and fibrinolysis impediment before and after treatment and comparing them with the healthy control group （ 50 cases ） .Results：The two treated groups had blood coagulation and fibrinolysis impediment of different levels before treatment （ P 〈 0.05 ） ,of which the smoking group was obvious than the non-smoking group （ P 〈 0.05 ） After treatment,the non-smoking group was better than the smoking group,with effective rate 88.2% and improvement of blood coagulation and fibrinolysis impediment.The difference of the two groups was statistically significant （P 〈 0.01 ） .Conclusion：Smoking was a cause to aggravate blood coagulation and fibrinolysis impediment of rheumatoid arthritis,had bad effects on its treatment and prognosis
出处
《风湿病与关节炎》
2013年第9期11-14,共4页
Rheumatism and Arthritis
关键词
关节炎
类风湿
凝血与纤溶障碍
吸烟
arthritis,rheumatoid
blood coagulation and fibrinolysis impediment
smoking
