摘要
目的研究花都地区孕妇早中晚期甲状腺功能变化。方法选择广州市花都区的孕妇作为观察组,进一步分为早期妊娠组、中期妊娠组、晚期妊娠组,选择非孕妇女作为对照组,检测甲状腺功能指标三碘甲状腺原氨酸(TT3)、总甲状腺素(TT4)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)及促甲状腺激素(TSH)的水平。结果早期妊娠组孕妇的甲状腺功能指标TT3、TT4、FT3、FT4与对照组的差异无统计学意义(P>0.05),TSH水平低于对照组、差异有统计学意义(P<0.05);中期妊娠组和晚期妊娠组TT3、TT4、FT3、FT4水平均低于对照组,TSH水平高于对照组、差异有统计学意义(P<0.05)。结论妊娠早期孕妇甲状腺功能无明显变化,妊娠中晚期时甲状腺激素水平显著降低,需要在临床中采取检查措施以及时发现、进而保证胎儿的正常发育。
Objective To study the thyroid function changes at early, medium and late stage for pregnant women in Huadu district. Methods The pregnant women in Huadu district of Guangzhou city were selected as the observation group,and were further divided into early pregnancy group,medium pregnancy group and late pregnancy group. The non-pregnant woman were selected as the control group.The thyroid function indexes were detected,such as the levels of triiodothyronine（TT3）,total thyroxine（TT4）,free triiodothyronine（FT3）,free thyroxine（FT4） and thyroid- stimulating hormone（TSH）. Results Compared with the control group,the differences were not statistically significant in TT3,TT4,FT3,FT4 of pregnant women in early pregnancy group（P 〉 0.05）,while the TSH level of pregnant women in early pregnancy group was lower,the difference was statistically significant（P 〈 0.05）.The TT3,TT4,FT3,FT4 levels in medium pregnancy group and late pregnancy group were lower than those in the control group,while the TSH level was higher, the differences were statistically significant（P 〈 0.05）. Conclusion The thyroid function in early pregnant women are not significantly changed,the thyroid hormone level at medium and late pregnancy stage reduce significantly,so it is necessary to apply clinical inspection measures for early, find and further ensure the normal development of the fetus.
出处
《中国医药科学》
2013年第18期201-202,共2页
China Medicine And Pharmacy
关键词
妊娠
甲状腺功能
促甲状腺激素
Pregnancy
Thyroid function
Thyroid-stimulating hormone
