摘要
目的 了解食盐加碘后天津市区正常成人和 Graves病患者碘营养状况。方法 采用酸消化砷铈催化分光光度法测定 42名正常成人和 74名 Graves病患者的 2 4h尿碘含量 ,比较 2个组人群尿碘中位数和尿碘频数分布。结果 天津市食盐加碘后正常人和 Graves病患者尿碘中位数分别为 2 5 8.0μg/ 2 4h和 5 0 0 .0μg/ 2 4h,均明显高于天津市食盐加碘前的水平 ;有 2 1.5 %正常人和 5 0 .0 % Graves病患者尿碘值大于 5 0 0μg/ 2 4h。Graves病患者的尿碘水平明显高于正常成人 (P <0 .0 0 1)。 Graves病患者频数分布中尿碘高值所占比例较大 (P <0 .0 1)。结论 食用合格碘盐能纠正天津市居民的碘缺乏状态 ,目前天津市民的碘摄入量偏高 ,碘可能诱发
Objective To evaluate iodine nutrition status of healthy subjects and patients with Graves disease in Tianjin after the program of iodized salt supplementation.Methods The urinary iodine was measured by spectrophotometer in 42 healthy subjects and 74 patients with Graves disease.Results The median value of urinary iodine after iodine supplementation were 258.0 μg/24h and 500.0 μg/24h in normal subjects and patients respectively,which were higher than those before iodine supplementation.The value of urinary idoine in 21.5% of normal subjects and 50.0% of patients were over 500.0 μg/24h.Conclusions The iodine deficiency was corrected by the supplementation of iodzed salt,however the intake of iodine was higher among the population in Tianjin,which indicated that iodine might be a risk factor in the pathogenesis of Graves disease.
出处
《中国地方病学杂志》
CAS
CSCD
2000年第6期454-456,共3页
Chinese Jouranl of Endemiology
