摘要
目的：探讨氟喹诺酮类药物导致的不良反应发生的临床特点和分布规律.方法：收集我院在2010年1月-12月115例氟喹诺酮类药物所致不良反应的患者资料,采用回顾性分析方法,对数据总结分析.结果：氟喹诺酮类药物不良反应男性发生率明显高于女性（P ＜0.05）；38～58岁是氟喹诺酮类药物不良反应发生的主要年龄段,明显高于其他年龄段（P＜0.05）.不良反应临床表现以神经系统为主；38-58岁年龄段不良反应发生时间和恢复时间均明显高于其他年龄段（P＜0.05）.结论：临床应用氟喹诺酮类药物时要充分认识其不良反应发生情况,提高合理用药水平,预防不良反应,降低不良反应的发生率.
Objective： To evaluate fluoroquinotone adverse reactions caused by the clinical characteristics and distribution. Methods： A retrospective analysis of 115 patients of our hospital from January 2010 1 - 12 months, they were treated adverse reactions of fluoroquinolones in patients with clinical data, and data were analyzed. Results： Fluoroquinolone adverse reactions were significantly higher than the male rate of females （ P 〈 0. 05 ） ; 38 ~ 58 years of age is adverse reactions of fluoroquinolones main age groups, significantly higher than other age groups （ P 〈0.05）. Clinical manifestations of adverse reactions based mainly on the nervous system; 38 -58 age group adverse reaction time and recovery time were significantly higher than other age groups （ P 〈 0. 05 ）. Conclusions ： Fluoroquinolones should be fully under-stood adverse events, the clinician should improve clinical medication level and attention to the possible prevention of adverse reactions to re-duce the incidence of adverse reactions.
出处
《内蒙古中医药》
2013年第22期79-80,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
氟喹诺酮类药物
不良反应
临床特点
分布
fluoroquinolones
adverse reactions
clinical characteristics
distribution
