摘要
目的探讨纤维支气管镜局部灌洗沐舒坦治疗肺脓肿的临床效果及价值。方法对我院收治的78例肺脓肿患者,随机分为对照组和观察组。对照组采用常规治疗,观察组在常规治疗的基础上给予纤支镜局部灌洗给药治疗。结果观察组总有效率为92.31%,对照组总有效率为74.36%,观察组明显高于对照组,两组间差别有统计学意义(P<0.05)。观察组在症状、体征消失时间、住院时间等比较均明显优于对照组,差异有统计学意义(P<0.05)。不良反应比较,两组差异无统计学意义(P>0.05)。治疗后随访3~6个月,对照组复发率明显高于观察组(P<0.05)。结论应用纤支镜灌洗给药治疗急性肺脓肿具有临床疗效好,疗程短,治愈率高,不良反应少等优点,值得临床上推广应用。
Objective To integrative the clinical efficacy of local injection of ambroxol by bronchoscopy in the treatment of pulmonary abscess. Methods 78 patients with pulmonary abscess were randomly divided into the observation group (39 cases) and the con- trol group (39cases). All patients were given the conventional treatment, and the observation group was additionally treated with local injection of ambroxol by bronchoscopy. Results The total effective rate was 92. 31% in the observation group, which was significantly higher than 74. 36% in the control group ( P 〈 0. 05 ). The improvement of symptoms, signs, duration of hospital stay was more pronounced in the observation group than in the control group ( P 〈 0. 05 ). There was no significant difference on adverse reactions between the two groups ( P 〉 0.05 ), but the recurrence rate was significantly higher in the control group than in the observation group after 3 - 6 months' follow-up (P 〈0. 05). Conclusion The application of local injection of ambroxol by bronchoscopy has the advantages of good clinical curative effect, short treatment period, high cure rate, and few adverse reactions in the treatment of patients with acute pulmonary abscess, and it is worthy of widely clinical application.
出处
《临床肺科杂志》
2013年第11期2021-2023,共3页
Journal of Clinical Pulmonary Medicine
关键词
支气管镜
局部灌洗
肺脓肿
沐舒坦
bronchoscopy
local injection
intractable bacterial pneumonia
ambroxol