期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

金黄色葡萄球菌引发医院感染的分子流行病学特征 被引量：4

下载PDF
导出
摘要 目的:观察院内感染主要的金黄色葡萄球菌克隆及其特征。方法:从200例院内感染患者痰液分离出金黄色葡萄球菌样本,分析核糖基因型组成及特异的附属基因调节(agr)多态性和特有毒素。结果:200例样本中均未见万古霉素耐药性。不同的群体及不同的核糖基因型样本的抗生素耐药性不同,agrⅡ型等位基因是一种流行克隆,而agrⅠ型只存在于散发病例中。在68%的样本中发现LukD/LukE白细胞毒素基因。结论:最流行的核糖基因型对于几乎所有的抗生素均敏感,其中没有LukD/LukE基因。因此可能有其他未发现的因素造成流行克隆的院内感染。
作者 刘宝欣
机构地区 唐山工人医院呼吸内科
出处 《实用医学杂志》 CAS 北大核心 2013年第18期3062-3064,共3页 The Journal of Practical Medicine
关键词 金黄色葡萄球菌 核糖基因型 院内感染
分类号 R181.3 [医药卫生—流行病学]
  • 相关文献

参考文献2

二级参考文献26

  • 1樊最末,张立强.ICU病房病原菌的临床分析[J].实用医学杂志,2005,21(13):1473-1474. 被引量：3
  • 2彭振丽,罗彦丽,魏秋玲,申慧蓉,孟炜丽,董桂英,向艳君.ICU病房近三年病原菌调查分析[J].中国现代医药杂志,2007,9(4):52-55. 被引量：3
  • 3戴良成,吴昊,劳志刚,茹晃耀,王素宁.重症监护病房下呼吸道感染细菌的构成及耐药性分析[J].实用医学杂志,2007,23(13):2057-2059. 被引量：10
  • 4Gruson D, Hibert G, Vargas F, et al. Strategy of antibiotic rotation:long term effect on incidence and susceptibilities of Gram-negative bacilli responsible for ventilator associated pneumonia [J]. Crit Care Med, 2003,3(7) : 1908-1914.
  • 5Giblin T B, Sinkowitz-Cochran R L, Harris P L, et al. Clinicians'perceptions of the problem of antimierobial resistance in health care facilities [J]. Arch Intern Med, 2004, 164( 15): 1662-1668.
  • 6Ahmed A. Al-Amiery,Abdul Amir H. Kadhum,Abu Bakar Mohamad,Danijela Maksimovi?-Ivani?.Antifungal and Antioxidant Activities of Pyrrolidone Thiosemicarbazone Complexes[J]. Bioinorganic Chemistry and Applications . 2012
  • 7Ziyad A. Taha,Abdulaziz M. Ajlouni,Waleed Al Momani,Abeer A. Al-Ghzawi.Syntheses, characterization, biological activities and photophysical properties of lanthanides complexes with a tetradentate Schiff base ligand[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy . 2011 (1)
  • 8Hiroshi Nikaido.Multidrug Resistance in Bacteria[J]. Annual Review of Biochemistry . 2009
  • 9A. A. Osowole,G. A. Kolawole,O. E. Fagade.Synthesis, characterization and biological studies on unsymmetrical Schiff-base complexes of nickel(II), copper(II) and zinc(II) and adducts with 2,2’-dipyridine and 1,10-phenanthroline[J]. Journal of Coordination Chemistry . 2008 (7)
  • 10David Savage,Nicola Neary,Gwen Malone,Steven R. Alley,John F. Gallagher,Peter T.M. Kenny.The synthesis and structural characterization of novel N - meta -ferrocenyl benzoyl amino acid esters[J]. Inorganic Chemistry Communications . 2005 (5)

共引文献14

同被引文献38

  • 1甲氧西林耐药的金黄色葡萄球菌肺炎诊治与预防专家共识[J].中国医学前沿杂志（电子版）,2013,5(1):45-50. 被引量：26
  • 2Ho-Su L, Sung Koo L, Do HP, et al. Emergence of muhidrug resistant infection in patients with severe acute pancreatitis [J]. Pancreatology,2014, 14(6) :450-453.
  • 3Cheng H, Yuan W, Zeng F, et al. Molecular and phenotypic evidence for the spread of three major methicillin-resistant Staphylococcus aureus clones associated with two characteristic antimicrobial resistance profiles in China [J]. J Antimicrob Chemother, 2013,68 ( 11 ), 2453-2457.
  • 4Van R, Adler DG. Acute pancreatitis:review and clinical update [J]. Hosp Physician, 2009,45 ( 1 ) : 9-19.
  • 5Badalov N, Baradarian R, Iswara K, et al. Drug-induced acute pancreatitis: an evidence-based review Gastroenterol Hepatol, 2007,5 (6) : 648-661.
  • 6Zhang Y, Gao SL, Zhang SY, et al. Six cases of severe acute pancreatitis complicated with vancomycin-resistant enterococcus enteritis [J]. Shock, 2014,42(5) :400-406.
  • 7Chert H, Liu Y, Jiang X, et al. Rapid change of methicillin- resistant Staphylococcus aureus clones in a Chinese tertiary care hospital over a 15-year period [J]. Antimicrob Agents Chemother, 2010,54(5) : 1842-1847.
  • 8Zhang W, Shen X, Zhang H, et al. Molecular epidemiological analysis of methicillin-resistant Staphylococcus aureus isolates from Chinese pediatric patients [J]. Eur J Clin Microbiol Infect Dis, 2009,28(7) : 861-864.
  • 9Clinical and Laboratory Standard Institute. Performance Standards for Antimicrobial Disk Susceptibility Tests; ~ffteon information supplement. Supplement. Clinical and Laboratory Standards Institute (formerly NCCLS ) [ M ]. 9 thed. Wayne :PA ,2014:44-49.
  • 10Reitzel R, Rosenblatt J, Jiang Y, et al. Disposable gendine antimicrobial gloves for preventing transmission of pathogens in health care settings [ J]. Am J Infect Control ,2014,42 (1) :55-59.

引证文献4

二级引证文献13

实用医学杂志
2013年 第18期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部