摘要
目的 分析我院呼吸机相关性肺炎（VAP）的病原学特点及耐药情况.方法 对我院综合重症监护室和呼吸重症监护室2011年1月至2012年8月诊断为VAP的44例患者病原学资料进行回顾性分析.结果 44例患者支气管分泌物培养获得致病菌83株,其中革兰阴性杆菌63株,占75.9％；革兰阳性球菌14株,占16.9％；真菌6株,占7.2％.革兰阴性杆菌中占前6位的分别是鲍曼不动杆菌、嗜麦芽窄食单胞菌、铜绿假单胞菌、肺炎克雷伯菌、产吲哚黄杆菌、阴沟肠杆菌；革兰阳性球菌主要是金黄色葡萄球菌.所分离菌株均不同程度表现多重耐药.结论 VAP的主要病原菌为革兰阴性杆菌,常为多重耐药的致病菌,临床医师应根据病原菌学及抗菌药物敏感性资料,及时选择合理的抗生素控制感染,延缓耐药菌株的产生.
Objective To investigate the distribution and drug resistance of pathogens from ventilator-associated pneumonia （VAP） in general intensive care unit （GICU） and respiratory intensive care unit（RICU）. Methods Etiological data of 44 patients who were diagnosed as VAP from January 2011 to August 2012 in GICU and RICU were analyzed retrospectively. Results A total of 83 pathogens were isolated. 63 strains （75.9%） were gram-negative bacillus, the main bacteria of which were Acinetobacter baumannii, Stenotrophomonas maltophilia, Pseudomonas aeruginosa, Klebsiella pneumoniae, Flavobacterium indologenes, and Enterobacter cloacae. 14 strains （16.9%） were gram- positive coccus, the main bacteria of which was Staphylococcus aureus. Six fungi strains were isolated （7.2%）. The strains isolated were multidrug resistant and had high resistance rate. Conclusions The main bacterium in patients with VAP is gram-negative bacillus, which has higher resistance to common antibiotics. According to the data of the pathogens and antibiotic susceptibility, we can select antibiotics reasonably to control the infection and delay the emergency of new drug-resistant bacteria.
出处
《国际呼吸杂志》
2013年第18期1383-1386,共4页
International Journal of Respiration
关键词
呼吸机相关性肺炎
病原菌
耐药性
Ventilator-associated pneumonia
Pathogen
Antibiotic resistance
