摘要
目的比较我国6大行政区域的肺功能预计值，探讨统一国内肺功能预计值公式的可行性。方法收集2011年8月至2012年3月在复旦大学附属中山医院的健康体检者资料，符合测定条件的360例，男女各半。以华东地区的预计值为标准，与华北、东北、西北、西南和华南地区的肺活量（VC）、用力肺活量（FVC）、第1秒用力呼气容积（FEV1）、一秒率（FEV1／FVC）的预计值，以及美国高加索人FVC、FEV1预计值乘以不同亚裔校正系数（0．88、0．94）的两种预计值进行比较研究。结果华东地区男性VC的预计值（4．19±0．33）L，与其他地区预计值的相关系数（r）为0．803～0．983，差异率为1．90％～4．30％。FVC为（4．06±0．35）L，r值为0．912～0．981，除与华南地区差异率为8．10％外，与其他地区的差异率为（0—2．46）％，与美国亚裔（×0．88及×0．94）的差异率分别为1．97％和4．68％。FEV，为（3．34±0．40）L，r值为0．963—0．992，与华北、东北地区差异率分别为0．9％、3．59％，与西南、华南地区差异率〉5％，与美国亚裔（×0．88及×0．94）差异率分别为6．89％、0．6％。FEV．／FVC为（80．87±3．84）％，r值为0．989～0．999，与华北、东北、华南地区差异率为（0．42～3．04）％，与西北、西南地区差异率〉5％。华东地区女性VC的预计值为（3．00±0．33）L，与其他地区的r值为0．899～0．993，差异率为0．33％～3．67％。FVC（2．92±0．34）L，与其他地区的r值为0．929—0．990，差异率为（1．02～2．40）％，与美国亚裔（×0．88及×0．94）差异率分别为4．79％、6．16％。FEV1为（2．38±0．39）L，r值为0．958—0．994，与东北、西南、华南地区差异率为0．84％～3．36％，与华北地区差异率为7．19％，与美国亚裔（X0．88及×0．94）差异率分别为2．10％和4．62％。FEV1／FVC为（82．04±3．94）％，r值为0．991—1．000，除西南地区差异率为7．59％外，与其他地区差异率为1．34％～4．55％。结论各区域间VC、FVC的预计值公式一致，华北、东北、华南与华东地区间FEV1／FVC的预计值公式一致，各地FEV1的预计值公式差别较大。国外预计值公式皆不适合国情，不同类型的参数可能需要不同的校正系数。
Objective To investigate the differences between six parts of China in prediction models of lung function. Methods The predicted values of 360 healthy volunteers underwent pulmonary function test in east China were compared with that of north China, northeast China, northwest China, southwest China, south China and Asian American. Results In the male group, the prediction values of east China were as follows：VC （4. 19 ＋ 0. 33 ）L, coefficient correlation（r） to the other five regions were 0. 803-0. 983, the differences to the other five regions were 1.90% -4. 30% ; FVC （ 4. 06±0. 35 ） L, r to the others were 0. 912-0. 981 ,the differences to the other four regions were 0-2.46% except for south China of 8. 10% , to Asian American x 0. 88 and Asian American x 0. 94 were I. 97% and 4. 68% ; FEVI （ 3.34±0. 40 ） L, r to the others were 0. 963-0. 992, the differences to north China and east China were 0. 9% and 3.59% , to southwest China and south China were 〉5% , to Asian American x0. 88 and Asian American x0. 94 were 6. 89% and 0. 6% ;FEV1/FVC （80. 87±3.84）%, r to the others were 0. 989-0. 999, the differences to north China,northeast China and south China were 0. 42%-3.04% ,to the others were 〉 5%. In the female group,the prediction values of east China were as follows：VC （3.00±0. 33 ）L, r to the other five regions were 0. 899-0. 993, the differences to the other five regions were 0. 33%-3.67% ;FVC （2. 92 ±0. 34）L,r to the other five regions were 0. 929-0. 990, the differences to the other five regions were 1.02%-2.40% , to Asian American x0. 88 and Asian Ameriean x0. 94 were 4. 79% and 6. 16% ;FEVI （2. 38 ＋0. 39） L,r to the other five regions were 0. 958-0. 994, the differences to northeast China, southwest China, south China were 0. 84%-3.36% ,to north china was 7.19% , to Asian American x0.88 and Asian American ~ 0. 94 were 2. 10% and 4. 62% ;FEVJFVC （82. 04±3.94 ）% , r to the others were 0. 991-1. 000, the differenee s to the other four regions were 1.34%-4. 55% exeept for southwest China was 7.59%. Conclusions VC and FVC predicted values are eoineident between six parts of China. FEVI/FVC predieted values are eoineident in the four parts of China exeept for westnorth and westsouth China. FEV1 predicted values are different. The oversea predicted values should be used with appropriate eonversion factors.
出处
《中国呼吸与危重监护杂志》
CAS
2013年第5期489-493,共5页
Chinese Journal of Respiratory and Critical Care Medicine
基金
上海市科学技术委员会科技发展基金(编号:09411951300)
关键词
肺功能参数
预计值
相关性
差异率
Pulmonary function test
Predieted value
Coeffieient correlation
Differenee rate
