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1-单取代-1,2,3-三唑环的构建进展 被引量:5

Advances in the Construction of 1-Monosubstituted1,2,3-Triazole Ring
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摘要 随着1,2,3-三唑衍生物应用范围的扩大,该类化合物的合成在近几年引起了广泛关注并获得了快速发展.1-单取代-1,2,3-三唑衍生物比其他类型三唑的杂环构建难度大,主要原因是合成该类产物"炔源"的结构要求独特,并需要相应特殊的反应条件.综述了该类杂环的构建研究进展,按照"炔源"的种类不同分别阐述了各种构建方法,主要包括乙炔、取代乙炔、乙烯化物等,并对部分重要的反应机理进行了分析. As the 1,2,3-triazole derivatives were used in many expanding areas, its preparation has attracted much attention and obtained encouraging progress in recent years. The construction of the ring of monosubstituted 1,2,3-triazoles is more difficult than that of the other kinds of these heterocycles, owing to the special request for the structure of "alkyne source" and the relatively rigorous reaction conditions required in the system. This review covers the recent construction advances of the heterocycles based on the different moieties, such as acetylene, substituted acetylene, vinyl compounds, and others. Some important mechanisms were also discussed in details.
出处 《有机化学》 SCIE CAS CSCD 北大核心 2013年第9期1884-1890,共7页 Chinese Journal of Organic Chemistry
基金 国家自然科学基金(No.21262020) 云南省科技厅(No.KKSY201207047)资助项目~~
关键词 1-单取代 1 2 3-三唑 乙炔 取代乙炔 乙烯化物 1-monosubstituted 1,2,3-triazoles acetylene substituted acetylene vinyl compounds
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  • 1董卫莉,赵卫光,李玉新,刘征骁,李正名.“链接”化学及其应用[J].有机化学,2006,26(3):271-277. 被引量:15
  • 2李研,巨勇,赵玉芬.氮杂唑合成反应在生物缀合物研究中的应用[J].有机化学,2006,26(12):1640-1646. 被引量:2
  • 3李凌君,博士论文,北京大学,北京,2007.
  • 4Fang, L.; Zhang, G.; Li, C.; Zheng, X.; Zhu, L.; Xiao, J.J.; Szakacs, G.; Nadas, J.; Chan, K. K.; Wang, R G.; Sun, D. J. Med. Chem. 2006, 49, 932.
  • 5Zhang, G.; Fang, L.; Zhu, L.; Sun, D.; Wang, R G. Bioorg. Med. Chem. 2006, 14, 426.
  • 6L'Abbe, G. Chem. Rev. 1969, 69, 345.
  • 7Huisgen, R. In 1,3-Dipolar Cycloaddition Chemistry, Ed.: Padwa, A., Wiley, New York, 1984, pp. 1-176.
  • 8Huisgen, R. Angew. Chem., Int. Ed. 1963, 2, 565.
  • 9Tornoe, C. W.; Christensen, C.; Meldal, M. Z Org. Chem. 2002, 67, 3057.
  • 10Rostovstev, V. V.; Green, L. G.; Fokin, V. V.; Sharpless, K. B. Angew. Chem., Int. Ed. 2002, 41, 2596.

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  • 1黄南平,钟平.叠氮基吡啶及1-吡啶基-1,2,3-三氮唑的合成[J].化学试剂,2005,27(5):276-278. 被引量:1
  • 2Niu J J,Zhou H,Li Z G,et al. An Efficient Ullmann-typeC-0 bond formation catalyzed by an air-stable copper( I)-bipyridyl complex[ J]. J Org C/iem,2008,73( 19) :7 814-7 817.
  • 3Salvi L,Davis N R, Ali S Z,e. al. A new biarylphosphineligand for the Pd-catalyzed synthesis of diaryl ethers undermild conditions[ J] . Org Lett ,2012,14( 1) ; 170-173.
  • 4Cristau H J,Cellier,P P, Hamada S,eJ al. A General andmild Ullmann-type synthesis of diaryl ethers[ J] . Org Lett,2004,6(6) :913-916.
  • 5Chelucci G. Synthesis and metal-catalyzed reactions ofgem-dihalovinyl systems [ J ]. Chem Rev .2012,112 ( 3 ) : 1344-1 462.
  • 6Wang J R, Manabe K. Transition-metal-catalyzed site-se-lective cross-coupling of di-and polyhalogenated compound[J] . Synthesis ,2009,9: 1 405-1 427.
  • 7Chelucci G, Capitta F, Baldinoa Sfet al. One-pot conver-sion of 1,1-dibromoalkenes into internal alkynes by se-quential Suzuki-Miyaura and dehydrobromination reactions[J]. Tetrahedron Lett,2(X)7,48(37) :6 514-6 517.
  • 8Rahimi A, Schmidt A. Tandem Suzuki-Miyaura cross-cou-pling/dehydrobromination of 1,1 -dibromoalkenes to al-kynes with a cyclobutene-1,2-diylbis( imidazolium) salt ascatalyst precursor [ J ]. Synthesis, 2010,15 : 2 621 -2 625.
  • 9ZhaoM,Kuang C X,Yang Qret al. Cs2C03-mediated syn-thesis of terminal alkynes from 1,1 -dibromo-1 -alkenes[J]. Tetrahedron Lettt2011,52(9) :992-994.
  • 10Ma D W, Cai Q. iV,_/V-Dimethyl glycine-promoted ullmanncoupling reaction of phenols and aryl halides [ J ]. OrgLeM,2003,5(21) :3 799-3 802.

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