摘要
越来越多的证据显示,血清促甲状腺激素（TSH）是预测结节性甲状腺肿患者发生甲状腺癌的独立危险因素.即使血清TSH水平在正常范围内,结节性甲状腺肿患者发生甲状腺癌的风险也随着血清TSH水平的升高而逐渐增加.高水平的TSH与甲状腺癌的高发生率以及晚期甲状腺癌关系密切.血清TSH抑制治疗能降低肿瘤进展高危患者的复发率和死亡率.血清TSH在甲状腺癌的发展过程中起着非常重要的作用.
More and more evidence showed that serum thyroid stimulating hormone（TSH） was an independent predictor for the diagnosis of thyroid cancer in patients with thyroid nodular goiter.In patients with thyroid nodular goiter,the risk of thyroid cancer increases with serum TSH level,and even TSH level within normal ranges,higher TSH level is associated with a higher frequency and more advanced stage of thyroid cancer.TSH suppression therapy can reduce thyroid carcinoma-related mortality and recurrence rate in high risk patients.TSH plays a key role in the development of thyroid cancer.
出处
《国际内分泌代谢杂志》
北大核心
2013年第5期318-320,324,共4页
International Journal of Endocrinology and Metabolism
基金
全军医学科技＂十二五＂科研项目（CWS11J063）
关键词
促甲状腺激素
甲状腺癌
甲状腺结节
Thyroid stimulating hormone
Thyroid cancer
Thyroid nodule
