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羊水过少的病因学及危险因素分析 被引量:13

Analysis on etiology and risk factors of oligohydramnion
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摘要 目的:探讨孕产妇羊水过少出现的病因并对其进行相关数据分析,同时寻找正确的临床治疗方法,从而降低围产儿死亡率。方法:B超诊断羊水指数(AFI)和收集并估测羊水总量法确定的羊水过少的妊娠妇女,随机选择1 000例入观察组,随机选取羊水正常妇女1 000例入对照组,从病因、妊娠及分娩期并发症、妊娠结局的临床资料进行对照分析。结果:临床中羊水过少与发生分娩方式的关系统计,羊水过少的孕妇难产率显著高于对照组,差异有统计学意义(P<0.01)。在妊娠期高血压疾病、过期妊娠、妊娠期肝内胆汁淤积症、新生儿窒息、生长受限、胎儿宫内窘迫、羊水粪染、脐带绕颈、死胎等指标上,观察组的发生率高于对照组,差异皆有统计学意义(P<0.05),过期妊娠、妊娠期肝内胆汁淤积症、妊娠期高血压疾病为出现羊水过少的危险因素。结论:羊水过少因主要为胎儿因素、胎盘因素、胎膜,主要危险因素为过期妊娠、妊娠期肝内胆汁淤积症、妊娠期高血压疾病,临床上要对以上因素引起重视,积极有效地纠正羊水过少。 Objective: To explore the causes of oligohydramnion, analyze the related data, find out the correct clinical therapy, and reduce perinatal mortality. Methods: A total of pregnant women with oligohydramnion diagnosed by amniotic fluid index (AFI) and total amount detection of amniotic fluid were selected as observation group; 1 000 pregnant women with normal amount of amniotic fluid were designed as control group. Thc clinical data including etiology, pregnancy complications, and pregnant outcome were compared and analyzed. Results: The incidence rate of difficult labor in observation group was statistically significantly higher than that in control group ( P 〈 0.01 ) . The incidence rates of hypertensive disorder complicating pregnancy (HDCP), prolonged pregnancy, intrahepatic cholestasis of pregnancy (ICP), neonatal asphyxia, fetal growth restriction, fetal distress, meeoniumstaining amniotic fluid, umbilical cord around neck, and stillbirth in obsercation group were statistically significantly higher than those in control group ( P 〈 0. 05 ) ; prolonged pregnancy, ICP, and HDCP were risk factors of oligohydramnion. Conclusion : The main causes of oligohydramnion include fetal factors, placental factors, and fetal membrane; the main risk factors of oligohydramuion are prolonged pregnancy, ICP, and HDCP; the above -mentioned factors should be paid more attention to actively and effectively correct oligohydramnion.
出处 《中国妇幼保健》 CAS 北大核心 2013年第29期4784-4786,共3页 Maternal and Child Health Care of China
基金 山东省科学技术发展计划项目〔2012GSF12136〕
关键词 羊水过少 围产期结局 围产儿 妊娠并发症 Oligohydramnion Perinatal outcome Perinatal infant Pregnancy complication
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