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放射性131I对甲状腺功能亢进伴白细胞减少患者的影响 被引量:4

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摘要 目的探讨放射性31I治疗伴有白细胞减少的甲状腺功能亢进患者对白细胞的影响。方法使用放射性31I治疗45例伴有白细胞减少的甲状腺功能亢进患者,观察治疗前及治疗后7d、3个月外周血白细胞、粒细胞、淋巴细胞及单核细胞计数的变化。结果治疗前[白细胞(3.44±1.56)×109/L,粒细胞计数(2.12±1.25)×109/L]、治疗7d[自细胞计数(7.21±2.01)×109/L,粒细胞计数(5.24±1.24)×109/L]、治疗3个月[白细胞计数(5.64±1.78)×109/L,粒细胞计数(3.68±1.32)×109/L]患者白细胞、粒细胞计数比较差异均有统计学意义(F=86.49,P:0.00;F=14.87,P=0.00),且治疗7d、3个月均显著高于治疗前,差异均有统计学意义(P均〈0.01);淋巴细胞治疗7d呈明显减低(P〈0.01),治疗后3个月上升至治疗前水平;单核细胞计数治疗前、后均无明显变化,差异均无统计学意义。结论放射性”’I在伴有白细胞减少的甲状腺功能亢进患者中不会导致白细胞计数减少,反而可在放射性”’l治疗后1周内获得白细胞计数的升高,并于治疗后较长时期内维持在正常范围。
作者 张力
出处 《中国综合临床》 2013年第10期1053-1054,共2页 Clinical Medicine of China
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