摘要
背景与目的近20年来,中国肺癌的发病水平呈明显上升趋势,但其性别和城乡发病差异以及平均发病年龄的变化趋势并不清楚。本研究将对1989年-2008年中国肺癌发病率在性别、城乡差异和平均发病年龄的变化趋势进行分析。方法利用全国1989年-2008年肿瘤登记地区的肺癌发病数据和人口数据,按照不同性别、不同地区(城乡)分层,运用Poisson回归模型和线性回归模型,分析发病率的性别比值、城乡比值和平均发病年龄的变化特征。结果和1989年相比,2008年肺癌发病率男女比值由2.47降低到了2.28,城乡比值由2.07下降到了1.14,男性平均发病年龄由65.32岁升高到了67.87岁,女性平均发病年龄由65.14岁升高到了68.05岁。肺癌发病的男女差异和城乡差别逐渐缩小,平均发病年龄逐年升高,变化趋势均有统计学意义。结论近20年,中国肺癌发病的性别和城乡差异明显缩小,发病年龄趋于老龄化,应针对肺癌发病现状开展更有效的防治研究工作。
Background and objective The lung cancer incidence was significantly increased in the past two decades in China.But the secular trend of lung cancer incidence difference between gender（male and female）,area（urban and rural） and average age was not clear.The aim of this study is to analyze the trend of lung cancer incidence rate ratio between gender,area and average age in China during 1989-2008,and provide some inspiration for lung cancer prevention and control activities.Methods Cancer registry data and population data in China from 1989 to 2008 were collected by the National Cancer Registration Center.Stratified for gender and area,Poisson regression model was used to estimate annual lung cancer incidence rate ratio between male and female,urban and rural areas.The average age of lung cancer incidence was calculated.Linear regression was used to model the trend of annual incidence rate ratio and average age over time.Results Incidence rate ratios of lung cancer between male and female,urban and rural areas were significantly decreased from 2.47 and 2.07 to 2.28 and 1.14 during 1989-2008,respectively.Meanwhile,the average age of lung cancer incidence among male and female dramatically increased from 65.32 and 65.14 to 67.87 and 68.05,respectively.Conclusion The difference of lung cancer incidence between male and female,urban and rural areas remarkably decreased from 1989 to 2008.The average age of lung cancer occurrence gradually increased.Researches,prevention and control activities on lung cancer with consideration of new incidence pattern should be strengthened.
出处
《中国肺癌杂志》
CAS
北大核心
2013年第9期445-451,共7页
Chinese Journal of Lung Cancer
