摘要
目的:观察新型宫内节育器(IUD)MYCu IUD和MCuⅡ功能性IUD(MCuⅡIUD)的避孕效果与安全性。方法:在本所门诊选择自愿使用IUD避孕的妇女,随机信封法分别放置MYCu IUD和MCuⅡIUD各200例,放置后1、3、6、12、24个月随访。结果:放置满24个月时,MYCu IUD和MCuⅡIUD的继续使用率分别为90.5/百妇女年、88.5/百妇女年;带器妊娠率分别为1.01/百妇女年、1.56/百妇女年;脱落率分别为1.05/百妇女年、1.04/百妇女年;因出血/疼痛取出率分别为2.06/百妇女年、2.59/百妇女年,差异均无统计学意义(P>0.05)。放置后1、3个月MYCu IUD不良反应(主要是月经异常和疼痛)发生率少于MCuⅡ组(P<0.05)。结论:MYCu IUD与MCuⅡIUD具有避孕效果好、脱落率低、安全的特点,含吲哚美辛的MYCu IUD可减少放置初期的不良反应,是当前比较理想的IUD。
Objective：To explore clinical effects and safety of MYCu intrauterine device （IUD） and MCu Ⅱ functional IUD （MCu Ⅱ IUD）.Methods：A total of 400 women seeking for IUD insertion for contraception in the outpatient department were divided into MYCu IUD group （n =200） and MCu Ⅱ IUD group （n =200） with a random envelope method and followed up at the 1st,3rd,6th,12nd,and 24th month after insertion.Results：Twenty-four months after insertion,90.5/100 women year and 88.5/100 women year in MYCu IUD group and MCu Ⅱ IUD group persisted on use,respectively.Rates of pregnancy with IUD in situ were 1.01/100 women year and 1.56/100 women year,respectively.Expulsion rates were 1.05/100 women year and 1.04/100 women year,respectively.And discontinuation rates due to bleeding/pain were 2.06/100 women year and 2.59/100 women year,respectively.There were no significant differences in indicators mentioned above between two groups.One month and 3 months after insertion,the occurrence rate of adverse effects （mainly abnormal menstruation and pain） of MYCu IUD group was significantly lower than that of MCu Ⅱ IUD group （P ＜ 0.05）.Conclusion：MYCu IUD and MCu Ⅱ IUD have the characteristics of better contraceptive effect,lower expulsion rate and less adverse effects.Indomethacin-containing MYCu IUD is a comparative ideal IUD because it can reduce eht incidence of adverse effects during early insertion.
出处
《中国计划生育学杂志》
2013年第9期603-606,共4页
Chinese Journal of Family Planning
关键词
宫内节育器
吲哚美辛
临床对照研究
Intrauterine device Indomethacin
Clinical comparative study
