摘要
目的探讨呼吸科重症监护室(ICU)老年患者导管相关性血流感染(CRBSI)的危险因素。方法对我院呼吸科ICU中诊断为CRBSI的老年患者进行筛选。对选出的20例患者,采用病例对照的研究方法进行风险因素回顾性分析。对照组为同期呼吸科ICU住院的行深静脉置管但无CRBSI的病例。结果两组对比显示基础疾病构成、年龄、性别、感染前导管留置时间、机械通气、完全肠外营养、尿管留置等指标差异无统计学意义(P>0.05)。CRBSI组使用碳青霉烯类抗生素、操作熟练程度、碳青酶烯类抗生素、置管部位、低白蛋白血症、贫血、APACHEII评分与对照组比较差异有统计学意义。多因素Logistic回归分析显示使用碳青霉烯类抗生素、操作者、低白蛋白血症、APACHEII评分是独立危险因素。结论碳青霉烯类抗生素使用、操作者人员熟练程度、低白蛋白血症及APACHEII评分是呼吸科ICU老年患者评估CRBSI的独立危险因素。
Objective To explore the risk factors of central venous catheter related bloodstream infections （CRBSI） in respiratory intensive care unit. Methods Respiratory ICU elderly patients diagnosed as CRBSI were screened to analysis retrospectively. Patients in the same period of hospitalization without catheter-related bloodstream infections were enrolled as control. Results There were 20 patients diagnosed as CRBSI, and 20 patients were enrolled as control. Result of comparison shows that underlying disease, age, gender, catheter-days, mechanical ventilation, total parenteral nutrition, and indwelling catheter were not significantly different （P〉0. 05）. Carbapenem antibiotic use, proficiency in operation, catheter site, hypo-albuminuria, anemia, APACHEⅡ score were significantly different between the groups. Multiple Logistic regression analysis shows that use of carbapenems, operation, hypo albuminuria, and APACHEⅡ score were independent risk factors. Conclusion Use of carbapenems, operation, hypo-albuminuria, APACHEⅡ score were risk factors of CRBSI in respiratory ICU elderly patients.
出处
《成都医学院学报》
CAS
2013年第4期384-387,共4页
Journal of Chengdu Medical College
基金
国家自然科学基金项目(NO:81270130)
关键词
中心静脉导管相关性血流感染
危险因素
呼吸重症监护室
Central venous catheter related bloodstream infections
Risk factors
Respiratoryintensive careunit
