摘要
目的了解浙江省衢州市钩端螺旋体(钩体)病疫情流行特征,为制定防治对策提供参考依据。方法用描述性流行病学方法对衢州市2001-2012年钩体病流行特征进行分析,用显微镜凝集试验,对临床确诊病例和宿主动物血清进行抗体测定;采集鼠、蛙、鸭、猪肾和牛中段尿,进行病原体分离培养;采集鼠、蛙肾进行钩体聚合酶链反应监测。结果衢州市2001-2012年钩体病年平均发病率为0.27/10万,发病以夏秋季为高发季节,以青壮年农民为主,男性高于女性,病例血清分型以黄疸出血群为主;宿主动物病原学监测阳性率为0.56%,以黄疸出血群和秋季热群为主;宿主动物血清抗体阳性率为17.79%,以黄疸出血群及秋季热群为主,分别占50.00%和28.30%。结论衢州市钩体病防治工作仍然不能放松,在洪涝灾害后,应列为防制重点,并继续加强对宿主动物和人群的监测,注意菌群变动。
Objective To investigate the epidemiological characteristics of leptospirosis in Quzhou, Zhejiang province, from 2001 to 2012, and provide scientific evidence for the prevention and treatment of leptospirosis. Methods Descriptive epidemiological analysis was conducted on the incidence data of leptospirosis in Quzhou during this period. The serum antibody detections of the diagnosed patients and host animals were conducted with microscopic agglutination test. The kidneys of mice, frogs, ducks and pigs as well as the mid stream urine of cattle were collected for the pathogen isolation. The kidneys of mice and frogs were collected to detect leptospira with PCR. Results The average annual incidence of leptospirosis in Quzhou was 0. 27/lakh from 2001 to 2012. The disease mainly occurred in summer and autumn. Most cases were middle-aged farmers, and more cases occurred in males than in females. The serological detection indicted that the major pathogen in the patients was L. icterohemorrhagie. The positive rate of pathogen detection in host animals was 0. 56%, the major pathogens were L. icterohearnorrhagiae and L. autumnalias. The serum positive rate was 17.79% in host animals, the major pathogens were L. icteroheamorrhagiae （ 50. 00% ） and L. autumnalias （28.30%）. Conclusion Close attention still should be paid to the prevention and treatment of leptospirosis in Quzhou, especially after flood disaster. It is necessary to strengthen the surveillance of leptospirosis both in human and in host animals.
出处
《疾病监测》
CAS
2013年第9期726-729,共4页
Disease Surveillance
关键词
钩端螺旋体
流行病学
监测
leptospirosis
surveillance
epidemiology
