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妊娠合并甲状腺功能减退72例临床分析 被引量:22

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摘要 目的 研究妊娠合并甲状腺功能减退(简称甲减)的患病情况、合并症、妊娠结局及治疗方法.方法 选取本溪市中心医院2009年1月~2012年12月妊娠合并甲状腺功能减退患者72例,给予左旋甲状腺素治疗;以妊娠晚期TSH< 3.0.IU/mL为治疗目标,分为控制组和未控组各36例.选取同期甲状腺功能正常孕妇72例为对照组.对三组临床资料进行回顾性分析与比较.结果 本组妊娠合并甲减的患病率为0.88%.妊娠期糖尿病发生率未控组高于对照组(P<0.05),控制组与对照组相比差异无统计学意义;妊娠合并子痫前期发生率未控组高于控制组(P<0.05);胎膜早破发生率甲减未控组、控制组与对照组相比差异均无统计学意义;早产、胎儿缺氧、胎儿畸形、剖宫产率及新生儿甲减发生率未控组均高于对照组(P均<0.05),而控制组与对照组相比无统计学差异.结论 在妊娠前及妊娠早期应对可能发生甲减的高危人群进行甲状腺功能筛查;对于妊娠合并甲减患者给予左旋甲状腺素治疗,可有效降低妊娠合并症及并发症的发生率,改善不良妊娠结局.
作者 王立媛 陈颖
机构地区 本溪市中心医院
出处 《山东医药》 CAS 2013年第36期68-70,共3页 Shandong Medical Journal
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共引文献173

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