摘要
目的:分析2010—2012年我院中药注射剂致药品不良反应(ADR)的发生情况、特点及规律,以指导临床合理使用中药注射剂。方法:采用回顾性研究方法,对2010年1月—2012年12月我院上报国家ADR监测中心的72例中药注射剂ADR进行统计、分析。结果:中药注射剂ADR的临床表现多样,主要为皮肤及其附件损害,为56例次,占总例次数的59.6%;新的一般的ADR为18例,占25%,严重的ADR较少,为3例,占4.2%;西医科室上报ADR的比例较大,为50例,占69.4%。结论:临床应重视中药注射剂不良反应的发生,合理选择溶剂,避免可能引起不良反应的联合用药,以提高合理用药水平。
ABSTRACT OBJECTIVE：To analyze the occurrence, characteristics and regularities of the adverse drug reactions （ADR） induced by traditional Chinese medicine injections in our hospital to guide clinical rational use of traditional Chinese medicine injections. METHODS： Using retrospective analysis, 72 ADR cases induced by traditional Chinese medicine injections submitted by our hospital to National ADR Monitoring Center from Jan. 2010 to Dec. 2012 were analyzed statistically. RESULTS： The adverse drug reactions （ADR） induced by traditional Chinese medicine injections in our hospital manifested differently, chiefly lesions of skin and its appendages, accounting for 59.6%. 18 （25%） were new and common ADR cases and 3 （4. 2% ） were serious ADR cases. ADR reports from departments of western medicine had larger proportion, accounting for 69.4%. CONCLUSION： Clinical importance should be attached to the ADRs induced by traditional Chinese medicine injections to achieve rational choice of solvents and avoid possible adverse reactions induced by drug combination so as to improve the level of rational use of drug.
出处
《中国医院用药评价与分析》
2013年第9期837-839,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
中药注射剂
不良反应
联合用药
Traditional Chinese medicine injections
Adverse drug reaction
Drug combination
