摘要
目的探讨埃索美拉唑联合莫沙必利治疗反流性食管炎的临床效果,以进一步指导临床治疗。方法选取本院收治的150例反流性食管炎患者进行研究,按照随机分组原则分为A、B、C 3组,每组各50例,A组患者采用单纯埃索美拉唑进行治疗,B组患者采用单纯莫沙必利进行治疗,C组患者采用埃索美拉唑联合莫沙必利进行治疗,观察和比较3组患者的治疗有效率。结果 A组患者治疗总有效率为78.0%,B组患者治疗总有效率为68.0%,C组患者治疗总有效率为88.0%,3组间差异有统计学意义(P<0.05),C组治疗效果最为显著。结论埃索美拉唑联合莫沙必利治疗反流性食管炎,临床效果显著,值得在临床推广应用。
Objective To investigate the clinical efficacy of esomeprazole combined with mosapride in the treatment of reflux esophagitis in order to further guide clinical treatment. Methods 150 patients with reflux esophagitis admitted to our hospital were selected and randomly divided into group A,group B and group C,with 50 cases in each group.Group A received single esomeprazole treatment,group B received single mosapride treatment,and group C received esomepra- zole combined with mosapride treatment.The treatment response rates of the three groups were observed and compared. Results The total treatment response rates of group A,group B and group C were 78.0%,68.0% and 88.0% respective- ly,with statistically significant difference among the three groups （P〈0.05）,and the treatment effect of group C was the most remarkable. Conclusion Esomeprazole combined with mosapride shows significant clinical effect in the treatment of reflux esophagitis,it is worthy of clinical promotion and application.
出处
《中国当代医药》
2013年第29期72-73,共2页
China Modern Medicine
