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基于三磷酸腺苷调节的分子马达单向能量跃迁模型 被引量:2

The single-direction energy transition model of molecular motor based on the control of adenosine triphosphate
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摘要 分子马达的梯跳运动和在过阻尼溶液中动力学原理尚未揭示清楚,从分子马达输运特点和实验现象出发,构建满足朗之万方程的单向能量跃迁模型,并通过Monte Carlo方法分析了分子马达的随机动力学行为.结果表明,在合适的跃迁能量作用下,分子马达可以利用噪声进行稳定的梯跳运动和有效的输运,但负载力会减弱分子马达系统的输运能力;轨道周期势虽影响分子马达速度的大小但不会改变其运动方向,分子马达运动方向由跃迁能量决定;另外,虽然在不同的噪声强度时平均速度不为零,但是分子马达系统的高效输运对噪声有一定选择性. The dynamic principle of molecular motor transport in overdamped solution remains unclear. Starting from the transport charac-teristics and phenomenon of the molecular motor system, the single-direction energy transition model is established, which conforms to the Langevin equation, and the stochastic dynamics of molecular motors is analyzed by Monte Carlo simulations. Results show that with the right transition energy, molecular motors could take a stable stepping motion and effective transport by means of the environment noise, and the load force can weaken material transportation of the molecular motor system. The potential field between a molecular motor and its orbit can affect the magnitude of the velocity of motor, but cannot change the direction of the velocity, the direction of motion of the molecular motor therefore is adjusted by the transition energy of the motor. In addition, although the average velocity is not zero for different noise intensities, the efficient transport of a molecular motor system indicates that the system is selective for the noise intensity.
出处 《物理学报》 SCIE EI CAS CSCD 北大核心 2013年第19期52-57,共6页 Acta Physica Sinica
基金 国家自然科学基金(批准号:10975045) 河北省教育厅科研基金(批准号:2008427c Z2012175) 张家口市科学技术研究项目(批准号:1101006B)资助的课题~~
关键词 分子马达 能量跃迁 朗之万方程 噪声强度 molecular motor, energy transition, langevin equation, noise intensity
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