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护理干预对化疗患者口腔黏膜炎的预防效果研究 被引量:8

Effect of nursing intervention on prevention of chemotherapy-induced oral mucositis
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摘要 目的探讨护理干预措施对化疗患者口腔黏膜炎的预防效果,寻找有效的护理方法,以降低化疗患者口腔黏膜炎的发生率。方法 310例接受化疗患者,随机分为试验组和对照组各155例,试验组实施健康教育、冰水含漱、测量口腔唾液pH值、pH纠正液含漱、口腔黏膜炎分级护理等干预措施,对照组为常规护理。结果试验组30例次发生口腔黏膜炎,发病率为19.35%,对照组为54.84%,两组间差异有统计学意义(P<0.05);试验组口腔黏膜炎各级别发病率依次为9.03%、5.81%、3.23%、1.29%,对照组分别为12.26%、20.00%、14.84%、7.74%;干预后,试验组口腔卫生状况明显好于对照组;化疗后,试验组102例患者口腔pH值为6.6~7.1,构成比占65.81%,明显高于对照组的3.89%(P<0.05)。结论综合护理干预可提高化疗患者预防口腔黏膜炎的意识,明显降低了化疗患者口腔黏膜炎的发病率。 OBJECTIVE To explore the effect of nursing intervention on prevention of chemotherapy-induced oral mucositis so as to find the effective nursing methods to reduce the incidence of chemotherapy-induced oral mucositis. METHODS Totally 310 patients who would receive chemotherapy were divided into the experimental group and the control group randomly. Each group was 150 cases. The nursing intervention measures included health education, ice water gargle, oral salivary pH measurement, pH adjustment of mouth, oral ulcer nursing according to the degree were implemented on the experimental group, meanwhile, the control group was treated with routine nursing care. RESULTS In the experimental group, 30 patients (19. 35 %) suffered chemotherapy- induced oral mucositis, lower than the control group (54.84%), the difference was significant (P^0.05). In the experimental group, the incidence of chemotherapy-induced oral mucositis of different degree were 9. 03%, 5.81%, 3. 23%, 1. 29%/00, respectively, while in the control group, they were 12. 26%, 20. 00%, 14. 84~/00, 7.74 %, respectively. Oral hygiene status in experimental group was obviously better than that in the control group after intervention, and there was 102 patients with oral pH value between 6.6 and 7.1 in the experimental group after chemotherapy, the proportion was 65. 81%, which was higher than control group (13 cases, 3. 89%) (P〈0.05). CONCLUSION Consciousness on the prevention of chemotherapy-induced oral mucositis of the patients has been improved by comprehensive nursing intervention, and the incidence of chemotherapy-induced oral mucositis has been reduced obviously.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2013年第19期4666-4668,共3页 Chinese Journal of Nosocomiology
基金 全军医学科研“十二五”计划课题(11BJZ28)
关键词 护理 干预 化疗 口腔黏膜炎 Nursing Intervention Chemotherapy Oral mucositis
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