摘要
目的：探讨在阴道分娩中预防性使用米索前列醇减少产后出血，降低产后出血率的有效性。方法：选择2012年1～12月足月妊娠阴道分娩产妇557例，随机分为治疗组和对照组。治疗组269例，在胎儿娩出后米索前列醇200μg舌下给药。对照组288例，不用米索前列醇。两组均在胎儿娩出后静点缩宫素10u，然后静点5％葡萄糖500ml＋缩宫素20u，持续4h。分析两组第三产程时间，产后2h及24h出血量，产后出血率。结果：治疗组第三产程时间（5．1±3．5）min、产后2h和产后24h出血量分别是（235．9±117．5）m1和（345．5±115．6）ml；对照组第三产程时间（10．3±4．2）min、产后2h和产后24h出血量分别是（323．7±128．1）m1和（481．7±151．9）ml。与对照组比较，治疗组第三产程时间、产后2h和产后24h出血量均少于对照组，差异均有统计学意义（P〈0．05）。治疗组产后出血6例，发生率2．2％；对照组产后出血13例，发生率4．5％。与对照组比较治疗组产后出血率低于对照组，差异均有统计学意义（P〈0．05）。结论：阴道分娩中预防性使用米索前列醇能减少产后出血降低产后出血率，与缩宫素联合使用比单纯使用缩宫素效果好。
Objective： To investigate the effectiveness of misoprostol which is used in vaginal delivery to prevent postpartum hemorrhage and decrease the rate of postpartum hemorrhage. Methods：We collected 557 ma- ture gravidas of vaginal delivery, between January 2012 and December 2012, and retrospectively divided them in- to treatment group and control group. There are 269 gravidas in treatment group, and 0.2rag misoprostol is sublingualed after fetal disengagement. There are 288 gravidas in control group, and misoprostol is not used af- ter fetal disengagement. Both in treatment group and control group 10 u oxytocin is dripped intravenous after re-tal disengagement, and 20 u is dripped intravenous persistantly 4hours after delivery. To analyze the hours of third stage of labor and the amount of bleeding 2hours after dilivery, 24hours after dilivery and the rate of hem- orrhage. Results：In treatment group the hours of third stage of labor and the amount of bleeding 2hours after dilivery, 24 hours after dilivery are（5.1 ± 3.5）rain, （235.9 ± 117.5）ml, （345.5 ± 115.6）ml. The hours of third stage of labor and the amount of bleeding 2 hours after dilivery, 24 hours after delivery in contro group are （10.3 ± 4.2）min, （323.7 ± 128.1）ml, （481.7 ± 151.9）ml. The hours of third stage of labor and the amount of bleeding are lower than that of control group, The difference was statistically significant（P〈0.05）. The hemor- rhage cases in treatmeng group are6, the rate is 2.2 % ; The hemorrhage cases in control group are13, the rate is 4.5 % ; The rate of hemorrhage of treatment group is lower than that of control group, The difference was statis- tically significant（ P （0.05）. Conclusion; Using misoprostol in vaginal delivery can decrease the amount of hem- orrhage, and reduce the rate of hemorrhage.
出处
《内蒙古医学杂志》
2013年第7期786-788,共3页
Inner Mongolia Medical Journal
关键词
米索前列醇
产后出血
阴道分娩
宫缩乏力
Misoprostol
Postpartum hemorrhage
Vaginal delivery
Uterine inertia
